Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ2 | O43526 | 2/20 | 0.45 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.31 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.31 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.31 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.30 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31020115 | 0.93 | KCNQ2 (0.47) | KCNQ2MAOBNR3C2GRIN2DGRIN3B | |
| SCHEMBL25290650 | 0.93 | KCNQ2 (0.47) | KCNQ2MAOBNR3C2GRIN2DGRIN3B | |
| SCHEMBL25775366 | 0.84 | KCNQ2 (0.52) | KCNQ2MAOBNR3C2MAPT | |
| SCHEMBL30487385 | 0.80 | KCNQ2 (0.46) | KCNQ2MAOBNR3C2MAPT | |
| SCHEMBL25250592 | 0.80 | KCNQ2 (0.46) | KCNQ2MAOBNR3C2MAPT | |
| SCHEMBL25246726 | 0.80 | KCNQ2 (0.57) | KCNQ2MAOBNR3C2GRIN2DGRIN3B | |
| Hydrochloric Acid SCHEMBL31546558 | 0.79 | KCNQ2 (0.56) | KCNQ2MAOBNR3C2GRIN2DGRIN3B | |
| SCHEMBL25246524 | 0.77 | KCNQ2 (0.50) | KCNQ2MAOBGRIN2DGRIN3BCHRM1 | |
| SCHEMBL30487403 | 0.77 | KCNQ2 (0.50) | KCNQ2MAOBGRIN2DGRIN3BCHRM1 | |
| SCHEMBL25246751 | 0.76 | KCNQ2 (0.78) | KCNQ2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118451079-A | Benzopiperidine derivative modulators, methods of preparation and uses thereof | 上海翰森生物医药科技有限公司 | 2024-08-06 | — | — | CN | disclosed |
| WO-2023125935-A1 | BENZOPYRIDINE DERIVATIVE REGULATOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海翰森生物医药科技有限公司 | 2023-07-06 | — | — | WO | disclosed |