Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TACR1 | P25103 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 3/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2527548 | 0.92 | KMT2A (0.46) | AOC3L3MBTL1KMT2ATDP1ATM | |
| SCHEMBL2527518 | 0.91 | PDGFRB (0.41) | AOC3L3MBTL1KMT2ATDP1BACE1 | |
| SCHEMBL2526966 | 0.87 | ABL1 (0.47) | L3MBTL1KMT2ACYP2D6ADRB2LMNA | |
| SCHEMBL2529626 | 0.86 | KMT2A (0.40) | L3MBTL1KMT2ATDP1ATMPPARG | |
| SCHEMBL2527448 | 0.85 | KMT2A (0.41) | AOC3L3MBTL1KMT2ATDP1ATM | |
| SCHEMBL2528951 | 0.85 | L3MBTL1 (0.42) | AOC3L3MBTL1KMT2ATDP1ATM | |
| SCHEMBL2528484 | 0.85 | AOC3 (0.42) | AOC3KMT2ACYP2D6BCHEADRB2 | |
| SCHEMBL2527806 | 0.85 | MEN1 (0.40) | AOC3L3MBTL1KMT2ATDP1 | |
| SCHEMBL2532005 | 0.85 | HSD17B10 (0.44) | AOC3L3MBTL1KMT2ATDP1LMNA | |
| SCHEMBL2526481 | 0.84 | L3MBTL1 (0.38) | AOC3L3MBTL1KMT2ATDP1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8039501-B2 | Synephrine derivatives useful as anti-inflammatory agents | UNIVERSITEIT GENT (BE) | 2011-10-18 | — | — | US | disclosed |
| US-20090029999-A1 | Synephrine derivatives useful as anti-inflammatory agents | UNIVERSITEIT GENT (BE) | 2009-01-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090029999-A1 | Synephrine derivatives useful as anti-inflammatory agents | HRH1, HRH3, HRH2 | AOC3 2105/4885L3MBTL1 4486/4885KMT2A 2317/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.