SCHEMBL25293270

SCHEMBL25293270

CCC(OCC1CO1)[Si](C)(Oc1ccccc1)Oc1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.49
ALDH1A1 P00352 3/20 0.42
GLA P06280 1/20 0.42
TP53 P04637 3/20 0.41
TSHR P16473 3/20 0.41
HIF1A Q16665 2/20 0.41
CYP3A4 P08684 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
MAPT P10636 2/20 0.34
HPGD P15428 2/20 0.34
CYP1A2 P05177 1/20 0.34
PPARG P37231 1/20 0.34
HRH3 Q9Y5N1 1/20 0.34
FGFR1 P11362 1/20 0.34
SRC P12931 1/20 0.34
CHRM2 P08172 2/20 0.33
CHRM4 P08173 2/20 0.33
CHRM5 P08912 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1949792 0.89 TDP1 (0.49) TDP1ALDH1A1GLATP53TSHR
SCHEMBL28469325 0.76 TDP1 (0.44) TDP1ALDH1A1GLATP53TSHR
SCHEMBL1461646 0.75 TDP1 (0.40) TDP1ALDH1A1GLATP53TSHR
SCHEMBL217440 0.75 ALDH1A1 (0.37) TDP1ALDH1A1GLATP53TSHR
SCHEMBL11682632 0.75 TDP1 (0.53) TDP1ALDH1A1GLATP53TSHR
SCHEMBL28552705 0.74 TDP1 (0.49) TDP1ALDH1A1GLATP53TSHR
SCHEMBL2732180 0.74 ALDH1A1 (0.37) TDP1ALDH1A1GLATP53TSHR
SCHEMBL50212 0.73 ALDH1A1 (0.36) TDP1ALDH1A1GLATSHRSMN1; SMN2
SCHEMBL285219 0.73 ALDH1A1 (0.36) TDP1ALDH1A1GLATSHRSMN1; SMN2
SCHEMBL28645988 0.73 TDP1 (0.41) TDP1ALDH1A1GLATP53TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4457284-A1 RUBBER FORMULATIONS COMPRISING FUNCTIONALIZED CONJUGATED DIENE POLYMER, NATURAL RUBBER, AND REINFORCING FILLER Bridgestone Corporation (JP) 2024-11-06 EP disclosed
WO-2023130014-A1 RUBBER FORMULATIONS COMPRISING FUNCTIONALIZED CONJUGATED DIENE POLYMER, NATURAL RUBBER, AND REINFORCING FILLER BRIDGESTONE CORPORATION (JP) 2023-07-06 WO disclosed