Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10415274 | 0.86 | ALDH1A1 (0.36) | ALDH1A1SMN1; SMN2TDP1TSHRMAPK1 | |
| SCHEMBL217440 | 0.84 | ALDH1A1 (0.37) | ALDH1A1SMN1; SMN2TDP1TSHRMAPK1 | |
| SCHEMBL21114734 | 0.82 | POLB (0.36) | ALDH1A1 | |
| SCHEMBL50212 | 0.82 | ALDH1A1 (0.36) | ALDH1A1SMN1; SMN2TDP1TSHRMAPK1 | |
| SCHEMBL329862 | 0.81 | ALDH1A1 (0.38) | ALDH1A1SMN1; SMN2TDP1TSHRMAPK1 | |
| SCHEMBL375726 | 0.81 | ALDH1A1 (0.33) | ALDH1A1SMN1; SMN2TDP1TSHRMAPK1 | |
| SCHEMBL1035031 | 0.81 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2TDP1TSHRMAPK1 | |
| SCHEMBL4313772 | 0.81 | SMN1; SMN2 (0.38) | ALDH1A1SMN1; SMN2TDP1TSHRMAPK1 | |
| SCHEMBL25287311 | 0.79 | SMN1; SMN2 (0.41) | ALDH1A1SMN1; SMN2TDP1TSHRMAPK1 | |
| SCHEMBL15513608 | 0.79 | ALDH1A1 (0.38) | ALDH1A1SMN1; SMN2TDP1TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8975357-B2 | Silicone modified fatty acids, method of preparation and usage thereof | NATURA INOVACAO E TECNOLOGIA DE PRODUTOS LTDA. (BR) | 2015-03-10 | — | — | US | claimed |
| EP-2620464-B1 | Silicone modified fatty acids, method of preparation and usage thereof | NATURA INOVAC O E TECNOLOGIA DE PRODUTOS LTDA (BR) | 2014-12-10 | — | — | EP | claimed |
| US-8846843-B2 | Silicone modified fatty acids, method of preparation and usage thereof | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2014-09-30 | — | — | US | claimed |
| EP-2473550-B1 | SILICONE MODIFIED FATTY ACIDS, METHOD OF PREPARATION AND USAGE THEREOF | MOMENTIVE PERFORMANCE MAT INC (US) | 2014-05-07 | — | — | EP | claimed |
| US-20130317105-A1 | SILICONE MODIFIED FATTY ACIDS, METHOD OF PREPARATION AND USAGE THEREOF | NATURA INOVACAO E TECNOLOGIA DE PRODUTOS LTDA. (BR) | 2013-11-28 | — | — | US | claimed |
| EP-2620464-A1 | Silicone modified fatty acids, method of preparation and usage thereof | Momentive Performance Materials Inc. (US) | 2013-07-31 | — | — | EP | claimed |
| US-20100040570-A1 | SILICONE MODIFIED FATTY ACIDS, METHOD OF PREPARATION AND USAGE THEREOF | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2010-02-18 | — | — | US | claimed |
| EP-3923038-A1 | OPTICAL ARTICLE WITH A DURABILITY IMPROVED HARD COATING | ESSILOR INTERNATIONAL (FR) | 2021-12-15 | — | — | EP | disclosed |
| US-20210380841-A1 | OPTICAL ARTICLE WITH A DURABILITY IMPROVED HARD COATING | ESSILOR INTERNATIONAL (FR) | 2021-12-09 | — | — | US | disclosed |
| EP-3602149-A1 | OPTICAL ARTICLE COMPRISING AN ABRASION- AND/OR SCRATCH-RESISTANT COATING HAVING A LOW SENSITIVITY TO CRACKS | Essilor International (FR) | 2020-02-05 | — | — | EP | disclosed |
| US-8975357-B2 | Silicone modified fatty acids, method of preparation and usage thereof | NATURA INOVACAO E TECNOLOGIA DE PRODUTOS LTDA. (BR) | 2015-03-10 | — | — | US | disclosed |
| WO-2014195401-A2 | PROCESS FOR THE PREPARATION OF SILICONE CONTAINING B-HYDROXYL ESTERS | DSM IP ASSETS B.V. (NL) | 2014-12-11 | — | — | WO | disclosed |
| EP-2620464-B1 | Silicone modified fatty acids, method of preparation and usage thereof | NATURA INOVAC O E TECNOLOGIA DE PRODUTOS LTDA (BR) | 2014-12-10 | — | — | EP | disclosed |
| US-5854147-A | Non-woven web containing antimicrobial siloxane quaternary ammonium salts | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 1998-12-29 | — | — | US | disclosed |
| US-5853641-A | Method for preparing polyolefin fibers containing antimicrobial siloxane quarternary ammonium salts | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 1998-12-29 | — | — | US | disclosed |
| US-5853883-A | Polyolefin fibers containing antimicrobial siloxane quaternary ammonium salts | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 1998-12-29 | — | — | US | disclosed |
| US-5777010-A | BLEND WITH THERMOPLASTIC POLYOLEFIN | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 1998-07-07 | — | — | US | disclosed |
| EP-0581082-B1 | Process for the preparation of surface-active anion-cation complexes | GOLDSCHMIDT AG TH (DE) | 1997-02-26 | — | — | EP | disclosed |
| US-5344949-A | Quaternary ammonium sulfonates from organoammonium hydrogen sulfite and epoxy compounds or organosilicon epoxy compounds | TH. GOLDSCHMIDT AG (DE) | 1994-09-06 | — | — | US | disclosed |
| EP-0581082-A1 | Process for the preparation of surface-active anion-cation complexes | Th. Goldschmidt AG (DE) | 1994-02-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130317105-A1 | SILICONE MODIFIED FATTY ACIDS, METHOD OF PREPARATION AND USAGE THEREOF | ASAH1, FASN, ASAH2 | ALDH1A1 1965/4885SMN1; SMN2 1507/4885TDP1 3646/4885 |
| US-20100040570-A1 | SILICONE MODIFIED FATTY ACIDS, METHOD OF PREPARATION AND USAGE THEREOF | FASN, ELOVL5, SCD5 | ALDH1A1 1282/4885SMN1; SMN2 2585/4885TDP1 4749/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.