Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.41 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.39 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | TNF | P01375 | 1/20 | 0.36 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30581438 | 1.00 | KMT2A (0.44) | KMT2AHDAC1HDAC8CXCR4TLR8 | |
| SCHEMBL30581408 | 0.81 | KMT2A (0.47) | KMT2ACXCR4TLR8NUDT1BACE1 | |
| SCHEMBL30586488 | 0.81 | JAK2 (0.53) | KMT2A | |
| SCHEMBL25252813 | 0.81 | JAK2 (0.53) | KMT2A | |
| SCHEMBL30581402 | 0.79 | KMT2A (0.67) | KMT2ACXCR4TLR8RAB9APOLB | |
| Nitrous Acid SCHEMBL25424540 | 0.79 | KMT2A (0.43) | KMT2ACXCR4TLR8NUDT1BACE1 | |
| SCHEMBL25302212 | 0.78 | KMT2A (0.47) | KMT2ACXCR4TLR8NUDT1BACE1 | |
| SCHEMBL8285688 | 0.75 | SOS1 (0.46) | KMT2ARAB9ASMN1; SMN2POLBTNF | |
| SCHEMBL4781011 | 0.73 | PTGER4 (0.61) | HDAC1HDAC8MAPTPOLBCXCR3 | |
| SCHEMBL8284643 | 0.72 | HTT (0.39) | KMT2AHDAC1HDAC8CXCR4TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023131333-A1 | BENZIMIDAZOLE COMPOUND AND MEDICAL USE THEREOF | 中国科学院上海药物研究所 | 2023-07-13 | — | — | WO | disclosed |