Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.43 |
| ▸ | AKT1 | P31749 | 4/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | MME | P08473 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TET3 | O43151 | 1/20 | 0.38 |
| ▸ | FBXL19 | Q6PCT2 | 1/20 | 0.38 |
| ▸ | CXXC5 | Q7LFL8 | 1/20 | 0.38 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.38 |
| ▸ | CXXC4 | Q9H2H0 | 1/20 | 0.38 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3032228 | 0.95 | AKR1C1 (0.47) | OPRM1AKR1C1AKT1HDAC1MME | |
| SCHEMBL28173281 | 0.83 | AKT1 (0.44) | OPRM1AKT1HDAC1MME | |
| SCHEMBL2221 | 0.82 | AKR1C1 (0.55) | AKR1C1HDAC1KMT2AMEN1TSHR | |
| SCHEMBL4005636 | 0.81 | DRD2 (0.58) | OPRM1AKR1C1AKT1KMT2ATET3 | |
| Hydrochloric Acid SCHEMBL28173275 | 0.81 | AKT1 (0.43) | OPRM1AKT1HDAC1MME | |
| SCHEMBL6498800 | 0.81 | OPRM1 (0.53) | OPRM1AKR1C1HDAC1KMT2AMEN1 | |
| SCHEMBL3910628 | 0.81 | AKR1C1 (0.53) | AKR1C1HDAC1KMT2AMEN1TSHR | |
| Hydrochloric Acid SCHEMBL4451578 | 0.80 | DRD2 (0.56) | OPRM1AKR1C1AKT1KMT2ATET3 | |
| SCHEMBL30711945 | 0.80 | AKT1 (0.45) | OPRM1AKT1HDAC1MMEKMT2A | |
| SCHEMBL10112796 | 0.79 | OPRM1 (0.51) | OPRM1AKT1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023132352-A1 | METHOD FOR PRODUCING AMIDE COMPOUND | 中外製薬株式会社 | 2023-07-13 | — | — | WO | disclosed |