Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIMK1 | P53667 | 5/20 | 0.39 |
| ▸ | LIMK2 | P53671 | 5/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HTR1D | P28221 | 5/20 | 0.38 |
| ▸ | HTR1B | P28222 | 5/20 | 0.38 |
| ▸ | QDPR | P09417 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | PARP1 | P09874 | 2/20 | 0.38 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30484043 | 0.86 | CNR1 (0.48) | ALK | |
| SCHEMBL31017627 | 0.86 | CNR1 (0.48) | ALK | |
| SCHEMBL25294762 | 0.81 | LIMK1 (0.33) | LIMK1LIMK2LMNAKMT2AMAPT | |
| SCHEMBL25830945 | 0.78 | BRD4 (0.48) | — | |
| SCHEMBL30484036 | 0.78 | BRD4 (0.48) | — | |
| SCHEMBL25262518 | 0.76 | LIMK1 (0.41) | LIMK1LIMK2SMN1; SMN2MEN1LMNA | |
| SCHEMBL28827483 | 0.74 | SMN1; SMN2 (0.40) | LIMK1LIMK2SMN1; SMN2MEN1LMNA | |
| SCHEMBL16262603 | 0.74 | QDPR (0.47) | SMN1; SMN2MEN1LMNAKMT2AHPGD | |
| SCHEMBL25252564 | 0.73 | KDM4E (0.52) | SMN1; SMN2MEN1LMNAKMT2AHPGD | |
| SCHEMBL28435263 | 0.73 | MAPT (0.50) | SMN1; SMN2MEN1LMNAKMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125907-A1 | DEGRADATION OF BRUTON'S TYROSINE KINASE (BTK) BY CONJUGATION OF BTK INHIBITORS WITH E3 LIGASE LIGAND AND METHODS OF USE | BEIGENE, LTD. (KY) | 2023-07-06 | — | — | WO | disclosed |