Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 4/20 | 1.00 |
| ▸ | SNCA | P37840 | 3/20 | 1.00 |
| ▸ | BCHE | P06276 | 1/20 | 1.00 |
| ▸ | TNF | P01375 | 1/20 | 0.97 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.97 |
| ▸ | MEN1 | O00255 | 2/20 | 0.94 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.94 |
| ▸ | RAB9A | P51151 | 2/20 | 0.94 |
| ▸ | NPC1 | O15118 | 1/20 | 0.94 |
| ▸ | POLB | P06746 | 1/20 | 0.94 |
| ▸ | INSR | P06213 | 9/20 | 0.59 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.40 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29350189 | 1.00 | APP (1.00) | APPSNCABCHETNFNOD1 | |
| SCHEMBL1577265 | 0.99 | APP (1.00) | APPSNCABCHETNFNOD1 | |
| Bromide SCHEMBL144934 | 0.97 | APP (0.97) | APPSNCABCHETNFNOD1 | |
| SCHEMBL8988031 | 0.89 | APP (0.81) | APPSNCABCHETNFNOD1 | |
| Hydrochloric Acid SCHEMBL39418 | 0.89 | APP (0.80) | APPSNCABCHETNFNOD1 | |
| SCHEMBL19305182 | 0.87 | APP (0.79) | APPSNCABCHETNFNOD1 | |
| Benzoic Acid SCHEMBL21436259 | 0.87 | APP (0.77) | APPSNCABCHETNFNOD1 | |
| Hydrochloric Acid SCHEMBL39277 | 0.85 | SNCA (0.74) | APPSNCABCHETNFNOD1 | |
| SCHEMBL19305181 | 0.83 | SNCA (0.73) | APPSNCABCHETNFNOD1 | |
| SCHEMBL21068083 | 0.83 | APP (0.72) | APPSNCABCHETNFNOD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 15938 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4427033-B1 | METHOD FOR QUALITATIVE AND QUANTITATIVE DETERMINATION OF PROTEIN AGGREGATES | PAIA BIOTECH GMBH (DE) | 2026-05-20 | — | — | EP | claimed |
| EP-4173696-B1 | EVALUATION METHOD FOR PROTEIN-CONTAINING SOLUTION | ASAHI KASEI LIFE SCIENCE CORP (JP) | 2026-05-20 | — | — | EP | claimed |
| CN-122060743-A | Fluorescent sensor based on G-quadruplex design and application thereof in detection of Abeta 42 | 上海大学 | 2026-05-19 | — | — | CN | claimed |
| US-20260133206-A1 | MISFOLDED PROTEIN DETECTION IN THE EYE | LACRISTAT LLC (US) | 2026-05-14 | — | — | US | claimed |
| US-12624096-B2 | Anti-tau antibodies and methods of use thereof | Gtinvent Limited (GB) | 2026-05-12 | — | — | US | claimed |
| US-12618856-B2 | Alpha-synuclein mutants and uses thereof | INDIAN INSTITUTE OF TECHNOLOGY BOMBAY (IN) | 2026-05-05 | — | — | US | claimed |
| US-20260118346-A1 | METHODS AND RELATED ASPECTS FOR DETERMINING COGNITIVE STATUS ASSOCIATED WITH PARKINSON'S DISEASE | UNIV JOHNS HOPKINS (US) | 2026-04-30 | — | — | US | claimed |
| EP-4733767-A2 | ALPHA-SYNUCLEIN DETECTION ASSAY AND METHOD FOR DIAGNOSING ALPHA-SYNUCLEINOPATHIES | The University Court Of The University of Edinburgh (GB) | 2026-04-29 | — | — | EP | claimed |
| US-20260078225-A1 | Polymerizable Compositions, Methods of Making a Polymer Using Same, and Products Thereof | UNIV CORNELL (US) | 2026-03-19 | — | — | US | claimed |
| EP-4705773-A2 | BIOSENSORS COMPRISING AMPHIPHILIC POLYMERS AND USE THEREOF | Sartorius BioAnalytical Instruments, Inc (US) | 2026-03-11 | — | — | EP | claimed |
| EP-0114462-B1 | DETECTION OF RETICULOCYTES | Becton Dickinson and Company (US) | 1986-04-09 | — | — | EP | claimed |
| US-4571388-A | Detection of reticulocytes | BECTON DICKINSON AND COMPANY (US) | 1986-02-18 | — | — | US | claimed |
| EP-0114462-A2 | Detection of reticulocytes | Becton Dickinson and Company (US) | 1984-08-01 | — | — | EP | claimed |
| US-4378277-A | AROMATIC IODONIUM COMPLEX SALT PHOTOINITIATOR; A PHOTOSENSITIZER | MINNESOTA MINING & MANUFACTURING COMPANY (US) | 1983-03-29 | — | — | US | claimed |
| US-4356050-A | Method of adhesive bonding using visible light cured epoxies | GENERAL ELECTRIC COMPANY (US) | 1982-10-26 | — | — | US | claimed |
| US-4308329-A | Manifold imaging method and materials | XEROX CORPORATION (US) | 1981-12-29 | — | — | US | claimed |
| EP-0003583-B1 | COMPOSITIONS FOR CYTOCHEMICAL INVESTIGATION, THEIR USE AND METHOD FOR THE DETECTION OF STEROID HORMONE RECEPTORS IN HUMAN TISSUES | Lee, Sin Hang (US) | 1981-12-02 | — | — | EP | claimed |
| US-4075015-A | Light sensitive mass and process for its production | SWISS ALUMINIUM LTD. (CH) | 1978-02-21 | — | — | US | claimed |
| US-4026705-A | EPOXY RESIN, ARYL IODONIUM SALT, CATIONIC DYE | GENERAL ELECTRIC COMPANY (US) | 1977-05-31 | — | — | US | claimed |
| US-3951654-A | CHARGE TRANSPORT SENSITIZER | XEROX CORPORATION (US) | 1976-04-20 | — | — | US | claimed |