Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 4/20 | 0.60 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.45 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.44 |
| ▸ | FEN1 | P39748 | 1/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | TLR4 | O00206 | 1/20 | 0.43 |
| ▸ | TLR2 | O60603 | 1/20 | 0.43 |
| ▸ | PRKDC | P78527 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.41 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | CDK9 | P50750 | 1/20 | 0.41 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17426491 | 0.83 | KDM4E (0.52) | GRM5CYP2A6TLR4TLR2PRKDC | |
| SCHEMBL11647426 | 0.83 | PTGER1 (0.53) | GRM5ALOX5APFEN1TRPA1PTGER1 | |
| SCHEMBL4777973 | 0.81 | KDM4E (0.50) | GRM5CYP2A6CYP1A2CYP2D6CYP19A1 | |
| SCHEMBL502867 | 0.79 | KDM4E (0.62) | GRM5CYP2A6TLR4TLR2CYP1A2 | |
| SCHEMBL29679578 | 0.79 | KDM4E (0.62) | GRM5CYP2A6TLR4TLR2CYP1A2 | |
| SCHEMBL2485206 | 0.79 | GRM5 (0.58) | GRM5CYP2A6TLR4TLR2CYP1A2 | |
| SCHEMBL15459106 | 0.78 | CYP2A6 (0.51) | GRM5CYP2A6TLR4TLR2PRKDC | |
| SCHEMBL15459120 | 0.78 | CYP2A6 (0.51) | GRM5CYP2A6TLR4TLR2PRKDC | |
| SCHEMBL2482401 | 0.78 | HRH3 (0.54) | CYP2A6TLR4TLR2CYP1A2CYP2D6 | |
| SCHEMBL17834278 | 0.78 | HRH3 (0.50) | GRM5CYP2A6TLR4TLR2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2378582-A1 | Stable and efficient electroluminescent materials | Universal Display Corporation (US) | 2011-10-19 | — | — | EP | disclosed |