SCHEMBL25299663

SCHEMBL25299663

CC(C)(C)OC(=O)N1CC2(C1)OCc1ccncc12

nearest known ligand 0.45

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
NR1H2 P55055 1/20 0.45
AVPR1A P37288 5/20 0.42
NAMPT P43490 6/20 0.41
GPR119 Q8TDV5 8/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30527626 1.00 NR1H2 (0.45) NR1H2AVPR1ANAMPTGPR119
SCHEMBL4065831 0.88 AVPR1A (0.51) AVPR1ANAMPTGPR119
SCHEMBL3223037 0.83 AVPR1A (0.53) NR1H2AVPR1ANAMPTGPR119
SCHEMBL30008913 0.83 AVPR1A (0.53) NR1H2AVPR1ANAMPTGPR119
SCHEMBL29871828 0.81 AVPR1A (0.45) AVPR1ANAMPT
SCHEMBL20502778 0.80 RORC (0.41) NR1H2AVPR1A
SCHEMBL15507949 0.79 NR1H2 (0.43) NR1H2AVPR1A
SCHEMBL15508228 0.77 NR1H2 (0.42) NR1H2AVPR1AGPR119
SCHEMBL16864998 0.77 AVPR1A (0.40) NR1H2AVPR1AGPR119
SCHEMBL12097232 0.76 RORC (0.40) NR1H2AVPR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250215029-A1 STAT MODULATORS AND USES THEREOF RECLUDIX PHARMA, INC. 2025-07-03 US disclosed
EP-4463459-A1 STAT MODULATORS AND USES THEREOF Recludix Pharma, Inc. (US) 2024-11-20 EP disclosed
CN-118804917-A STAT modulators and uses thereof 瑞克鲁迪克斯制药股份有限公司 2024-10-18 CN disclosed
WO-2023133336-A1 STAT MODULATORS AND USES THEREOF RECLUDIX PHARMA, INC. (US) 2023-07-13 WO disclosed
WO-2023133336-A1 STAT MODULATORS AND USES THEREOF RECLUDIX PHARMA, INC. (US) 2023-07-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250215029-A1 STAT MODULATORS AND USES THEREOF STAT6, STAT3, STAT5A NR1H2 926/4885AVPR1A 2684/4885NAMPT 1463/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.