Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 7/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3223037 | 1.00 | AVPR1A (0.53) | AVPR1AMAPK1NAMPTHRH3NR1H2 | |
| SCHEMBL3232343 | 0.90 | AVPR1A (0.57) | AVPR1AMAPK1HRH3 | |
| SCHEMBL3231066 | 0.88 | AVPR1A (0.54) | AVPR1AMAPK1HRH3 | |
| SCHEMBL16864998 | 0.84 | AVPR1A (0.40) | AVPR1ANR1H2GPR119ESR2 | |
| SCHEMBL20502778 | 0.84 | RORC (0.41) | AVPR1ANR1H2ESR2 | |
| SCHEMBL12097232 | 0.83 | RORC (0.40) | AVPR1ANR1H2ESR2 | |
| SCHEMBL21788515 | 0.83 | AVPR1A (0.45) | AVPR1ANR1H2ESR2 | |
| SCHEMBL12097185 | 0.83 | GPR119 (0.42) | AVPR1ANR1H2GPR119ESR2 | |
| SCHEMBL29716173 | 0.83 | RORC (0.40) | AVPR1ANR1H2ESR2 | |
| SCHEMBL25299663 | 0.83 | NR1H2 (0.45) | AVPR1ANAMPTNR1H2GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115210221-A | Isoxazoline derivatives as pesticides | 礼蓝动物保健有限公司 | 2022-10-18 | — | — | CN | disclosed |