Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.50 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 8/20 | 0.41 |
| ▸ | CES1 | P23141 | 5/20 | 0.41 |
| ▸ | CES2 | O00748 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | FNTA | P49354 | 1/20 | 0.39 |
| ▸ | FNTB | P49356 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2529890 | 1.00 | GPR84 (0.50) | GPR84FFAR1FFAR4KDM4ESMN1; SMN2 | |
| SCHEMBL25836002 | 1.00 | GPR84 (0.50) | GPR84FFAR1FFAR4KDM4ESMN1; SMN2 | |
| SCHEMBL2529981 | 0.97 | GPR84 (0.46) | GPR84FFAR1FFAR4KDM4ESMN1; SMN2 | |
| SCHEMBL2525666 | 0.90 | CAMK2A (0.46) | GPR84FFAR1FFAR4KDM4ESMN1; SMN2 | |
| SCHEMBL16722811 | 0.89 | FAAH (0.48) | GPR84FAAHCES1CES2MEN1 | |
| SCHEMBL19163900 | 0.89 | FAAH (0.48) | GPR84FAAHCES1CES2MEN1 | |
| SCHEMBL18751671 | 0.89 | FAAH (0.48) | GPR84FAAHCES1CES2MEN1 | |
| SCHEMBL13661862 | 0.89 | FAAH (0.48) | GPR84FAAHCES1CES2MEN1 | |
| SCHEMBL16640758 | 0.89 | FAAH (0.48) | GPR84FAAHCES1CES2MEN1 | |
| SCHEMBL12247043 | 0.89 | FAAH (0.48) | GPR84FAAHCES1CES2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8461135-B2 | Boron-containing small molecules as anti-inflammatory agents | ANACOR PHARMACEUTICALS, INC. (US) | 2013-06-11 | — | — | US | claimed |
| US-8039450-B2 | Boron-containing small molecules as anti-inflammatory agents | ANACOR PHARMACEUTICALS, INC. (US) | 2011-10-18 | — | — | US | claimed |