SCHEMBL25299869 — predicted protein targets

Predicted protein targets (top 10)

	gene	UniProt	supporting neighbours	confidence
▸	KAT2B	Q92831	9/20	0.38

▸	BPTF	Q12830	1/20	0.38

▸	IL1B	P01584	6/20	0.36

▸	NLRP3	Q96P20	5/20	0.36

▸	CCNT1	O60563	1/20	0.35

▸	CCNK	O75909	1/20	0.35

▸	CCNE1	P24864	1/20	0.35

▸	CDK2	P24941	1/20	0.35

▸	CDK9	P50750	1/20	0.35

▸	CDK12	Q9NYV4	1/20	0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL25294680	0.80	KAT2B (0.41)	KAT2BBPTFIL1BNLRP3
SCHEMBL25294648	0.80	KAT2B (0.45)	KAT2BBPTFIL1BNLRP3CCNT1
SCHEMBL25253097	0.80	KAT2B (0.41)	KAT2BBPTFIL1BNLRP3
SCHEMBL25294649	0.80	KAT2B (0.45)	KAT2BBPTFIL1BNLRP3CCNT1
SCHEMBL25856248	0.76	IL1B (0.52)	IL1BNLRP3
SCHEMBL29030548	0.76	IL1B (0.52)	IL1BNLRP3
SCHEMBL30488480	0.76	IL1B (0.52)	IL1BNLRP3
SCHEMBL30295360	0.73	NLRP3 (0.42)	IL1BNLRP3
SCHEMBL30517809	0.72	KAT2B (0.45)	KAT2BBPTFIL1BNLRP3CCNT1
SCHEMBL29042801	0.72	KAT2B (0.50)	KAT2BBPTFIL1BNLRP3CCNT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2023131277-A1	NLRP3 INFLAMMASOME INHIBITOR AND USES THEREOF	药捷安康(南京)科技股份有限公司	2023-07-13	—	—	WO	disclosed