Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.30 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.30 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.30 |
| ▸ | SLC6A12 | P48065 | 2/20 | 0.30 |
| ▸ | SLC6A11 | P48066 | 2/20 | 0.30 |
| ▸ | SLC6A13 | Q9NSD5 | 2/20 | 0.30 |
| ▸ | CCR5 | P51681 | 1/20 | 0.30 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.30 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.30 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3967283 | 0.85 | HTR2C (0.35) | — | |
| SCHEMBL32167197 | 0.81 | CCR5 (0.47) | CCR5 | |
| SCHEMBL24210962 | 0.79 | HTR2C (0.43) | HTR3ACCR5 | |
| SCHEMBL4213177 | 0.79 | HTR2C (0.39) | HTR3ACCR5 | |
| Hydrochloric Acid SCHEMBL32672841 | 0.78 | CCR5 (0.44) | CCR5 | |
| SCHEMBL18738154 | 0.74 | KCNH2 (0.31) | KCNH2 | |
| SCHEMBL27487228 | 0.71 | — | — | |
| SCHEMBL17006846 | 0.69 | — | — | |
| SCHEMBL17329451 | 0.69 | CCR5 (0.41) | CCR5 | |
| SCHEMBL1830086 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8232360-B2 | Stereoregular ROMP polymers | RESEARCH FOUNDATION OF STATE UNIVERSITY OF N.Y. (US) | 2012-07-31 | — | — | US | disclosed |
| US-20110251363-A1 | STEREOREGULAR ROMP POLYMERS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2011-10-13 | — | — | US | disclosed |
| WO-2008019217-A2 | STEREOREGULAR ROMP POLYMERS | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 2008-02-14 | — | — | WO | disclosed |
| WO-2005059098-A2 | METHODS AND COMPOSITIONS FOR TREATING AND/OR PREVENTING NEURODEGENERATIVE CONDITIONS | CREIGHTON UNIVERSITY (US) | 2005-06-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110251363-A1 | STEREOREGULAR ROMP POLYMERS | PCBP1, PARG, OSGEP | HTR3A 3624/4885KCNH2 4129/4885SLC6A1 3705/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.