Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK2 | O96017 | 4/20 | 0.41 |
| ▸ | NLRP3 | Q96P20 | 5/20 | 0.39 |
| ▸ | IL1B | P01584 | 3/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 4/20 | 0.38 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.38 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.38 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.35 |
| ▸ | CCNK | O75909 | 2/20 | 0.35 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.35 |
| ▸ | CDK2 | P24941 | 2/20 | 0.35 |
| ▸ | CDK9 | P50750 | 2/20 | 0.35 |
| ▸ | CDK12 | Q9NYV4 | 2/20 | 0.35 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.35 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.35 |
| ▸ | CDK7 | P50613 | 1/20 | 0.35 |
| ▸ | CCNH | P51946 | 1/20 | 0.35 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25301015 | 1.00 | CHEK2 (0.41) | CHEK2NLRP3IL1BCHEK1PDPK1 | |
| SCHEMBL30488558 | 0.96 | CHEK2 (0.40) | CHEK2NLRP3IL1BCHEK1PDPK1 | |
| SCHEMBL30488587 | 0.96 | CHEK2 (0.40) | CHEK2NLRP3IL1BCHEK1PDPK1 | |
| SCHEMBL29030533 | 0.96 | CHEK2 (0.40) | CHEK2NLRP3IL1BCHEK1PDPK1 | |
| SCHEMBL29030535 | 0.96 | CHEK2 (0.40) | CHEK2NLRP3IL1BCHEK1PDPK1 | |
| SCHEMBL25299853 | 0.82 | EHMT2 (0.37) | CHEK2NLRP3PDPK1RPS6KB1CCNT1 | |
| SCHEMBL25299854 | 0.82 | EHMT2 (0.37) | CHEK2NLRP3PDPK1RPS6KB1CCNT1 | |
| SCHEMBL31197274 | 0.82 | EHMT2 (0.37) | CHEK2NLRP3PDPK1RPS6KB1CCNT1 | |
| SCHEMBL25262878 | 0.82 | NLRP3 (0.42) | CHEK2NLRP3IL1BPDPK1RPS6KB1 | |
| SCHEMBL25302079 | 0.82 | NLRP3 (0.42) | CHEK2NLRP3IL1BPDPK1RPS6KB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250152584-A1 | NLRP3 INFLAMMASOME INHIBITOR AND USES THEREOF | TRANSTHERA SCIENCES (NANJING), INC. (CN) | 2025-05-15 | — | — | US | disclosed |
| EP-4461729-A1 | ANTIGEN BINDING PROTEIN TARGETING MSLN AND USE THEREOF | Transthera Sciences (Nanjing), Inc. (CN) | 2024-11-13 | — | — | EP | disclosed |
| WO-2023131277-A1 | NLRP3 INFLAMMASOME INHIBITOR AND USES THEREOF | 药捷安康(南京)科技股份有限公司 | 2023-07-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250152584-A1 | NLRP3 INFLAMMASOME INHIBITOR AND USES THEREOF | NLRP3, NLRP1, PYCARD | CHEK2 3752/4885NLRP3 1/4885IL1B 7/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.