SCHEMBL25304559

SCHEMBL25304559

COC(=O)Oc1c(OC)cccc1OC

nearest known ligand 0.53

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
NFE2L2 Q16236 2/20 0.53
HPGD P15428 4/20 0.52
KDM4E B2RXH2 2/20 0.52
HSD17B10 Q99714 1/20 0.52
LMNA P02545 1/20 0.50
CA12 O43570 1/20 0.50
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
CA7 P43166 1/20 0.50
CA9 Q16790 1/20 0.50
CA14 Q9ULX7 1/20 0.50
HTT P42858 1/20 0.46
KMT2A Q03164 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.45
GABRA1 P14867 2/20 0.44
GABRG2 P18507 2/20 0.44
GABRB3 P28472 2/20 0.44
GAA P10253 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1954243 0.91 CA12 (0.54) NFE2L2HPGDKDM4EHSD17B10LMNA
SCHEMBL9957520 0.87 NFE2L2 (0.43) NFE2L2HPGDKDM4EHSD17B10LMNA
SCHEMBL1665129 0.84 SRC (0.59) NFE2L2HPGDKDM4ELMNACA1
SCHEMBL2160010 0.83 NFE2L2 (0.56) NFE2L2HPGDKDM4EHSD17B10LMNA
SCHEMBL2875254 0.82 MAPK1 (0.62) NFE2L2HPGDKDM4EHSD17B10LMNA
SCHEMBL15547744 0.81 NFE2L2 (0.47) NFE2L2HPGDKDM4ELMNACA12
SCHEMBL9791378 0.81 ELANE (0.46) NFE2L2HPGDKDM4EHSD17B10LMNA
SCHEMBL15548892 0.81 GABRA1 (0.50) NFE2L2HPGDKDM4ELMNACA12
SCHEMBL982771 0.81 HSD17B10 (0.63) HPGDKDM4EHSD17B10CA12CA1
SCHEMBL3755885 0.81 MAPK1 (0.56) NFE2L2HPGDKDM4EHSD17B10LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4463501-B1 PROCESS FOR PREPARING A POLYCARBONATE BY FRIEDEL-CRAFTS ALKYLATION COVESTRO DEUTSCHLAND AG (DE) 2025-12-24 EP disclosed
EP-4463501-A1 PROCESS FOR PREPARING A POLYCARBONATE BY FRIEDEL-CRAFTS ALKYLATION Covestro Deutschland AG (DE) 2024-11-20 EP disclosed
CN-118541414-A Method for producing polycarbonates by friedel-crafts alkylation 科思创德国股份有限公司 2024-08-23 CN disclosed
WO-2023135105-A1 PROCESS FOR PREPARING A POLYCARBONATE BY FRIEDEL-CRAFTS ALKYLATION COVESTRO DEUTSCHLAND AG (DE) 2023-07-20 WO disclosed
EP-4212571-A1 PROCESS FOR PREPARING A POLYCARBONATE BY FRIEDEL-CRAFTS ACYLATION Covestro Deutschland AG (DE) 2023-07-19 EP disclosed