Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.80 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.65 |
| ▸ | PAM | P19021 | 2/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.56 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.56 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.56 |
| ▸ | NAAA | Q02083 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | HTR2C | P28335 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9245169 | 1.00 | DGKA (0.80) | DGKADNM1PAMTSHRMAPT | |
| SCHEMBL4623164 | 1.00 | DGKA (0.80) | DGKADNM1PAMTSHRMAPT | |
| SCHEMBL2528230 | 0.98 | DGKA (0.76) | DGKADNM1PAMTSHRMAPT | |
| SCHEMBL2532239 | 0.91 | DGKA (0.65) | DGKADNM1PAMTSHRMAPT | |
| SCHEMBL2532997 | 0.90 | DGKA (0.77) | DGKADNM1PAMTSHRMAPT | |
| SCHEMBL3323202 | 0.89 | DGKA (0.65) | DGKAMAPTLMNAALDH1A1DUSP3 | |
| SCHEMBL8154593 | 0.89 | DGKA (1.00) | DGKADNM1PAMTSHRMAPT | |
| Glycol Distearate SCHEMBL29407 | 0.89 | DGKA (1.00) | DGKADNM1PAMTSHRMAPT | |
| SCHEMBL1197282 | 0.89 | DGKA (1.00) | DGKADNM1PAMTSHRMAPT | |
| SCHEMBL813087 | 0.89 | DGKA (1.00) | DGKADNM1PAMTSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8461135-B2 | Boron-containing small molecules as anti-inflammatory agents | ANACOR PHARMACEUTICALS, INC. (US) | 2013-06-11 | — | — | US | claimed |
| US-8039450-B2 | Boron-containing small molecules as anti-inflammatory agents | ANACOR PHARMACEUTICALS, INC. (US) | 2011-10-18 | — | — | US | claimed |