Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.65 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.53 |
| ▸ | PAM | P19021 | 2/20 | 0.48 |
| ▸ | NAAA | Q02083 | 1/20 | 0.48 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2528230 | 0.93 | DGKA (0.76) | DGKADNM1PAMNAAAHTR2C | |
| SCHEMBL9245169 | 0.91 | DGKA (0.80) | DGKADNM1PAMNAAAHTR2C | |
| SCHEMBL4623164 | 0.91 | DGKA (0.80) | DGKADNM1PAMNAAAHTR2C | |
| SCHEMBL2530607 | 0.91 | DGKA (0.80) | DGKADNM1PAMNAAAHTR2C | |
| SCHEMBL2529870 | 0.89 | DGKA (0.63) | DGKADNM1PAMNAAAHTR2C | |
| Ethylene Glycol Dipentanoate SCHEMBL812973 | 0.88 | DGKA (0.82) | DGKADNM1PAMNAAAHTR2C | |
| SCHEMBL2525616 | 0.87 | DGKA (0.61) | DGKADNM1PAMNAAAHTR2C | |
| SCHEMBL2529046 | 0.86 | — | — | |
| SCHEMBL812772 | 0.86 | DGKA (0.71) | DGKADNM1PAMNAAAHTR2C | |
| SCHEMBL130610 | 0.86 | DGKA (0.71) | DGKADNM1PAMNAAAHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8461135-B2 | Boron-containing small molecules as anti-inflammatory agents | ANACOR PHARMACEUTICALS, INC. (US) | 2013-06-11 | — | — | US | claimed |
| US-8039450-B2 | Boron-containing small molecules as anti-inflammatory agents | ANACOR PHARMACEUTICALS, INC. (US) | 2011-10-18 | — | — | US | claimed |