SCHEMBL25307010

SCHEMBL25307010

ClCc1cccc(I)c1CCl

nearest known ligand 0.37

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.37
IDO1 P14902 2/20 0.35
ALDH1A1 P00352 1/20 0.33
TSHR P16473 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.32
GABRA1 P14867 1/20 0.31
GABRB2 P47870 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21768207 0.85 GABRA1 (0.46) TAAR1IDO1ALDH1A1TSHRGABRA1
SCHEMBL30831845 0.85 GABRA1 (0.46) TAAR1IDO1ALDH1A1TSHRGABRA1
SCHEMBL234202 0.82 TSHR (0.39) TAAR1IDO1ALDH1A1TSHRL3MBTL1
SCHEMBL21768199 0.81 TAAR1 (0.35) TAAR1IDO1GABRA1GABRB2
SCHEMBL30831840 0.81 TAAR1 (0.35) TAAR1IDO1GABRA1GABRB2
SCHEMBL1445634 0.77
SCHEMBL29437224 0.77
SCHEMBL21768187 0.76 TAAR1 (0.43) TAAR1TSHR
SCHEMBL30831843 0.76 TAAR1 (0.43) TAAR1TSHR
SCHEMBL20560228 0.74 TAAR1 (0.41) TAAR1ALDH1A1TSHRL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4463502-A1 PROCESS FOR PREPARING A POLYCARBONATE BY FRIEDEL-CRAFTS ALKYLATION Covestro Deutschland AG (DE) 2024-11-20 EP disclosed
WO-2023135106-A1 PROCESS FOR PREPARING A POLYCARBONATE BY FRIEDEL-CRAFTS ALKYLATION COVESTRO DEUTSCHLAND AG (DE) 2023-07-20 WO disclosed