Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PNMT | P11086 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5497771 | 0.87 | PNMT (0.48) | TSHRALDH1A1L3MBTL1PNMTTAAR1 | |
| SCHEMBL1048140 | 0.87 | ALDH1A1 (0.33) | TSHRALDH1A1L3MBTL1GABRA1GABRB2 | |
| SCHEMBL1539462 | 0.84 | TAAR1 (0.44) | PNMTTAAR1IDO1 | |
| SCHEMBL9524049 | 0.82 | HSPA5 (0.42) | TSHRALDH1A1L3MBTL1GABRA1GABRB2 | |
| SCHEMBL9806683 | 0.82 | SLC6A2 (0.36) | TSHRALDH1A1L3MBTL1 | |
| SCHEMBL25307010 | 0.82 | TAAR1 (0.37) | TSHRALDH1A1L3MBTL1GABRA1GABRB2 | |
| SCHEMBL5598362 | 0.82 | TAAR1 (0.37) | TSHRALDH1A1L3MBTL1GABRA1GABRB2 | |
| SCHEMBL6908927 | 0.80 | GABRA1 (0.44) | TSHRALDH1A1PNMTGABRA1GABRB2 | |
| SCHEMBL28945819 | 0.80 | PNMT (0.46) | TSHRALDH1A1PNMTTAAR1IDO1 | |
| SCHEMBL18550415 | 0.80 | ALDH1A1 (0.35) | TSHRALDH1A1L3MBTL1PNMTGABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3951888-A | Process for preparing polyoxyalkylene having allyl end-group | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JA) | 1976-04-20 | — | — | US | claimed |
| US-3948966-A | METAL CHLORIDE-DIMETHYLFORMAMIDE CATALYSTS | KAO SOAP CO., LTD. (JA) | 1976-04-06 | — | — | US | claimed |
| CN-116655686-A | Synthesis method and application of pentavalent and trivalent tridentate phosphine ligand | 广东欧凯新材料有限公司 | 2023-08-29 | — | — | CN | disclosed |
| EP-4077464-A2 | FREE RADICAL POLYMERIZABLE ADHESION-PROMOTING INTERLAYER COMPOSITIONS AND METHODS OF USE | PRC-Desoto International, Inc. (US) | 2022-10-26 | — | — | EP | disclosed |
| EP-4043091-A1 | INTERFACIAL POLYMERIZATION METHOD FOR PREPARING MEMBRANES | Universiteit Twente (NL) | 2022-08-17 | — | — | EP | disclosed |
| WO-2021127292-A2 | FREE RADICAL POLYMERIZABLE ADHESION-PROMOTING INTERLAYER COMPOSITIONS AND METHODS OF USE | PRC-DESOTO INTERNATIONAL, INC. (US) | 2021-06-24 | — | — | WO | disclosed |
| US-20200040018-A1 | AMINE SYNERGISTS | HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) | 2020-02-06 | — | — | US | disclosed |
| WO-2018143923-A1 | AMINE SYNERGISTS | HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) | 2018-08-09 | — | — | WO | disclosed |
| US-9745406-B2 | Curable composition | CEMEDINE CO., LTD. (JP) | 2017-08-29 | — | — | US | disclosed |
| EP-2412756-B1 | CURABLE COMPOSITION | CEMEDINE CO LTD (JP) | 2016-12-21 | — | — | EP | disclosed |
| EP-1967550-B9 | ROOM TEMPERATURE CURABLE SILICON GROUP-CONTAINING POLYMER COMPOSITION | MOMENTIVE PERFORMANCE MAT JP (JP) | 2016-11-09 | — | — | EP | disclosed |
| WO-2001058962-A1 | CONTINUOUS PROCESS FOR THE PRODUCTION OF CONTROLLED ARCHITECTURE MATERIALS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2001-08-16 | — | — | WO | disclosed |
| EP-0877766-A1 | PREPARATION OF BRANCHED POLYMERS | THE DOW CHEMICAL COMPANY (US) | 1998-11-18 | — | — | EP | disclosed |
| US-5700887-A | CONTACTING MONOMER WITH DIFUNCTIONAL ANIONIC INITIATOR TO FORM MACROMER, CONTACTING WITH MULTIFUNCTIONAL COUPLING AGENT, CONTACTING WITH TERMINATING AGENT | THE DOW CHEMICAL COMPANY (US) | 1997-12-23 | — | — | US | disclosed |
| WO-1997028201-A1 | PREPARATION OF BRANCHED POLYMERS | THE DOW CHEMICAL COMPANY (US) | 1997-08-07 | — | — | WO | disclosed |
| US-5130413-A | Forming a metal salt of the polyoxyalkylene oxide by reaction with alkali metal alkoxide and reaction with a halogen unsaturated compound | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1992-07-14 | — | — | US | disclosed |
| EP-0415404-A2 | Process for producing unsaturated group-terminated high-molecular weight polyalkylene oxide | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1991-03-06 | — | — | EP | disclosed |
| US-4187250-A | CROSSLINKING AGENTS FOR POLYURETHANES, POLYUREAS | M&T CHEMICALS INC. (US) | 1980-02-05 | — | — | US | disclosed |
| US-4059610-A | Process for preparing isocyanic acid derivatives | KAO SOAP CO., LTD. (JA) | 1977-11-22 | — | — | US | disclosed |
| US-3951888-A | Process for preparing polyoxyalkylene having allyl end-group | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JA) | 1976-04-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200040018-A1 | AMINE SYNERGISTS | PNMT, HNMT, MYB | TSHR 1689/4885ALDH1A1 1673/4885L3MBTL1 1222/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.