Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.32 |
| ▸ | BUB1 | O43683 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.30 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.30 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21408124 | 0.83 | KDM1A (0.41) | KDM1AUSP2SMN1; SMN2CTSKBUB1 | |
| SCHEMBL25311521 | 0.79 | KDM1A (0.36) | KDM1A | |
| SCHEMBL21408128 | 0.79 | KDM1A (0.40) | KDM1AUSP2SMN1; SMN2CTSKALDH1A1 | |
| SCHEMBL21408160 | 0.78 | CTSK (0.38) | KDM1AUSP2SMN1; SMN2CTSKBUB1 | |
| SCHEMBL21408149 | 0.75 | KDM1A (0.41) | KDM1AUSP2SMN1; SMN2CTSKPDE4A | |
| SCHEMBL21408133 | 0.74 | KDM1A (0.40) | KDM1AUSP2SMN1; SMN2CTSKSPHK1 | |
| SCHEMBL25248764 | 0.73 | KDM1A (0.40) | KDM1AUSP2SMN1; SMN2BUB1ALDH1A1 | |
| SCHEMBL21408167 | 0.72 | KDM1A (0.36) | KDM1AUSP2SMN1; SMN2CTSKPDE4A | |
| SCHEMBL18039806 | 0.71 | KDM1A (0.39) | KDM1AUSP2SMN1; SMN2BUB1ALDH1A1 | |
| SCHEMBL479856 | 0.70 | KDM1A (0.43) | KDM1AUSP2SMN1; SMN2CTSKBUB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118510776-A | Five-membered ring-containing derivative, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2024-08-16 | — | — | CN | disclosed |
| WO-2023134765-A1 | FIVE-MEMBERED-RING-CONTAINING DERIVATIVES, PREPARATION METHOD THEREFOR, AND USES THEREOF | 上海翰森生物医药科技有限公司 | 2023-07-20 | — | — | WO | disclosed |