SCHEMBL25307188

SCHEMBL25307188

Cc1ccc(C)c(NC(=O)N2CCN(c3cccc(O)c3)CC2)c1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 3/20 0.62
CA1 P00915 3/20 0.62
CA2 P00918 3/20 0.62
CA9 Q16790 3/20 0.62
LMNA P02545 2/20 0.53
RAB9A P51151 2/20 0.53
PANK3 Q9H999 1/20 0.50
KMT2A Q03164 3/20 0.49
TP53 P04637 2/20 0.49
GAA P10253 1/20 0.49
POLB P06746 3/20 0.48
CYP3A4 P08684 2/20 0.48
CYP2C19 P33261 2/20 0.48
MAPT P10636 2/20 0.48
MEN1 O00255 1/20 0.48
HCRTR1 O43613 1/20 0.48
USP2 O75604 1/20 0.48
CYP1A2 P05177 1/20 0.48
CYP2C9 P11712 1/20 0.48
MAPK1 P28482 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25263692 0.86 CA12 (0.59) CA12CA1CA2CA9LMNA
SCHEMBL25262859 0.86 KMT2A (0.67) CA12CA1CA2CA9LMNA
SCHEMBL6962601 0.81 RBP4 (0.57) CA12CA1CA2CA9LMNA
SCHEMBL25262619 0.80 MEN1 (0.47) RAB9AKMT2AMEN1MAPK1NPC1
SCHEMBL14372217 0.78 RAB9A (0.64) RAB9AKMT2ATP53GAAPOLB
SCHEMBL9057398 0.77 GAA (0.51) CA12CA1CA2CA9LMNA
SCHEMBL1575407 0.76 TP53 (0.63) LMNARAB9APANK3KMT2ATP53
SCHEMBL3682625 0.75 RAB9A (0.56) RAB9APANK3TP53GAACYP3A4
SCHEMBL27299347 0.75 MYC (0.63) LMNAKMT2APOLBMAPTMEN1
SCHEMBL25308364 0.74 CNR1 (0.48) RAB9AKMT2ATP53MAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4460492-A1 COMPOUNDS CONTAINING A HYDROXYPHENYL MOIETY AND THEIR USE (INSERM) Institut National de la Santé et de la Recherche Médicale (FR) 2024-11-13 EP claimed
WO-2023131677-A1 COMPOUNDS CONTAINING A HYDROXYPHENYL MOIETY AND THEIR USE INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) 2023-07-13 WO claimed
EP-4460492-A1 COMPOUNDS CONTAINING A HYDROXYPHENYL MOIETY AND THEIR USE (INSERM) Institut National de la Santé et de la Recherche Médicale (FR) 2024-11-13 EP disclosed
WO-2023131677-A1 COMPOUNDS CONTAINING A HYDROXYPHENYL MOIETY AND THEIR USE INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) 2023-07-13 WO disclosed
WO-2023131677-A1 COMPOUNDS CONTAINING A HYDROXYPHENYL MOIETY AND THEIR USE INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) 2023-07-13 WO disclosed