Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | PKM | P14618 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | AURKA | O14965 | 1/20 | 0.52 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | ELANE | P08246 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16377892 | 0.84 | PTGER4 (0.56) | ALDH1A1MAPTPOLBKMT2AMEN1 | |
| SCHEMBL9925003 | 0.82 | PTGDR2 (0.54) | ALDH1A1GAAMAPTLMNAL3MBTL1 | |
| SCHEMBL22609303 | 0.80 | PDE4D (0.53) | ALDH1A1GAAMAPTLMNAL3MBTL1 | |
| SCHEMBL25309590 | 0.80 | ALDH1A1 (0.64) | ALDH1A1PKMGAAMAPTLMNA | |
| SCHEMBL12933531 | 0.79 | ALDH1A1 (0.56) | ALDH1A1PKMGAALMNAPOLB | |
| SCHEMBL25313395 | 0.78 | ALDH1A1 (0.55) | ALDH1A1PKMGAAHTTAURKA | |
| SCHEMBL19402534 | 0.78 | ELANE (0.56) | ELANE | |
| SCHEMBL3793270 | 0.78 | MAPT (0.51) | ALDH1A1GAAMAPTHTTL3MBTL1 | |
| SCHEMBL16244384 | 0.78 | MAPT (0.51) | ALDH1A1PKMGAAMAPTKMT2A | |
| SCHEMBL31409773 | 0.77 | AURKA (0.55) | ALDH1A1PKMGAAMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023139536-A1 | (4-PIPERAZIN-1YL)-4-ALKYL-PHTHALAZIN-1(2H)-ONE COMPOUNDS AS PARP7 INHIBITORS | RHIZEN PHARMACEUTICALS AG (CH) | 2023-07-27 | — | — | WO | disclosed |