Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.54 |
| ▸ | ELANE | P08246 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13347985 | 0.90 | PTGDR2 (0.54) | PTGDR2MAPTL3MBTL1THRBLMNA | |
| SCHEMBL1217408 | 0.89 | L3MBTL1 (0.61) | PTGDR2ELANEL3MBTL1ALDH1A1MAPK1 | |
| SCHEMBL28098679 | 0.88 | PTGDR2 (0.54) | PTGDR2MAPTL3MBTL1THRBLMNA | |
| SCHEMBL10126761 | 0.87 | PTGDR2 (0.48) | PTGDR2MAPTL3MBTL1THRBLMNA | |
| SCHEMBL28007646 | 0.87 | PTGDR2 (0.51) | PTGDR2MAPTL3MBTL1THRBLMNA | |
| SCHEMBL10126774 | 0.86 | PTGDR2 (0.53) | PTGDR2MAPTL3MBTL1THRBLMNA | |
| SCHEMBL12311296 | 0.86 | PTGDR2 (0.47) | PTGDR2MAPTL3MBTL1THRBLMNA | |
| SCHEMBL9925002 | 0.85 | PTGDR2 (0.52) | PTGDR2MAPTL3MBTL1THRBLMNA | |
| SCHEMBL25307190 | 0.82 | ALDH1A1 (0.58) | ELANEMAPTL3MBTL1LMNAALDH1A1 | |
| SCHEMBL10126781 | 0.82 | PTGDR2 (0.47) | PTGDR2MAPTL3MBTL1THRBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012075678-A1 | SUBSTITUTED THIAZOLYL PYRAZOLO PYRIDINE COMPOUND AND MEDICINAL USE THEREOF | 中国人民解放军军事医学科学院毒物药物研究所 (CN) | 2012-06-14 | — | — | WO | disclosed |