Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | DHODH | Q02127 | 2/20 | 0.45 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25309226 | 0.87 | CDC7 (0.48) | ALDH1A1KDM4EHPGDHSD17B10LMNA | |
| SCHEMBL10027994 | 0.81 | KDM4E (0.59) | HTTALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL25306445 | 0.78 | CTSA (0.41) | KDM5B | |
| SCHEMBL28056374 | 0.77 | ALDH1A1 (0.47) | ALDH1A1KDM4EHPGDHSD17B10TDP1 | |
| SCHEMBL30282819 | 0.77 | ALDH1A1 (0.49) | HTTALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL22717705 | 0.77 | ALDH1A1 (0.49) | HTTALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL29573953 | 0.75 | SLC22A12 (0.53) | HTTALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL22717569 | 0.75 | SLC22A12 (0.53) | HTTALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL536179 | 0.74 | HTT (0.62) | HTTALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL22717614 | 0.74 | HTT (0.50) | HTTALDH1A1KDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023134708-A1 | THIAZOLOPYRIDYL AMIDE DERIVATIVES AS DNA POLYMERASE THETA INHIBITORS | BEIGENE , LTD. (KY) | 2023-07-20 | — | — | WO | disclosed |