SCHEMBL25308289

SCHEMBL25308289

CC(C)(C)OC(=O)N1CC(c2cnccc2C2OCCO2)C1

nearest known ligand 0.44

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ GPR119 Q8TDV5 12/20 0.44
▸ KDM4E B2RXH2 1/20 0.41
▸ IDO1 P14902 1/20 0.39
▸ HPGDS O60760 1/20 0.38
▸ USP30 Q70CQ3 1/20 0.38
▸ CYP2C9 P11712 1/20 0.37
▸ CCNK O75909 1/20 0.37
▸ CDK12 Q9NYV4 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30527606 1.00 GPR119 (0.44) GPR119KDM4EIDO1HPGDSUSP30
SCHEMBL25262540 0.85 GPR119 (0.54) GPR119KDM4EIDO1CYP2C9
SCHEMBL30527746 0.85 GPR119 (0.54) GPR119KDM4EIDO1CYP2C9
SCHEMBL25305154 0.83 GPR119 (0.49) GPR119KDM4EIDO1CYP2C9
SCHEMBL31250355 0.83 GPR119 (0.49) GPR119KDM4EIDO1CYP2C9
SCHEMBL25307728 0.82 GPR119 (0.46) GPR119KDM4EIDO1CYP2C9
SCHEMBL31066403 0.82 GPR119 (0.48) GPR119KDM4EIDO1CYP2C9
SCHEMBL25888794 0.81 GPR119 (0.62) GPR119KDM4EIDO1USP30
SCHEMBL25306751 0.81 GPR119 (0.52) GPR119KDM4EIDO1USP30
SCHEMBL31655197 0.80 GPR119 (0.49) GPR119KDM4EIDO1CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250215029-A1 STAT MODULATORS AND USES THEREOF RECLUDIX PHARMA, INC. 2025-07-03 — — US disclosed
EP-4463459-A1 STAT MODULATORS AND USES THEREOF Recludix Pharma, Inc. (US) 2024-11-20 — — EP disclosed
WO-2023133336-A1 STAT MODULATORS AND USES THEREOF RECLUDIX PHARMA, INC. (US) 2023-07-13 — — WO disclosed
WO-2023133336-A1 STAT MODULATORS AND USES THEREOF RECLUDIX PHARMA, INC. (US) 2023-07-13 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250215029-A1 STAT MODULATORS AND USES THEREOF STAT6, STAT3, STAT5A GPR119 399/4885KDM4E 1488/4885IDO1 1766/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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