SCHEMBL25888794

SCHEMBL25888794

CC(C)(C)OC(=O)N1CC(c2ccncc2F)C1

nearest known ligand 0.62

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ GPR119 Q8TDV5 9/20 0.62
▸ KDM4E B2RXH2 1/20 0.44
▸ SPR P35270 1/20 0.43
▸ GPBAR1 Q8TDU6 1/20 0.42
▸ ALOX5AP P20292 1/20 0.42
▸ FEN1 P39748 1/20 0.42
▸ IDO1 P14902 1/20 0.41
▸ BTK Q06187 1/20 0.41
▸ USP30 Q70CQ3 1/20 0.41
▸ ROCK2 O75116 1/20 0.41
▸ PRKG1 Q13976 1/20 0.41
▸ CYP3A4 P08684 1/20 0.41
▸ CYP3A5 P20815 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25306751 0.90 GPR119 (0.52) GPR119KDM4EGPBAR1ALOX5APFEN1
SCHEMBL12211412 0.88 GPR119 (0.76) GPR119KDM4EROCK2PRKG1
SCHEMBL31066403 0.86 GPR119 (0.48) GPR119KDM4ESPRIDO1
SCHEMBL25262540 0.85 GPR119 (0.54) GPR119KDM4ESPRALOX5APFEN1
SCHEMBL30527746 0.85 GPR119 (0.54) GPR119KDM4ESPRALOX5APFEN1
SCHEMBL31250355 0.84 GPR119 (0.49) GPR119KDM4EIDO1
SCHEMBL25305154 0.84 GPR119 (0.49) GPR119KDM4EIDO1
SCHEMBL25307728 0.83 GPR119 (0.46) GPR119KDM4EIDO1
SCHEMBL25888627 0.82 GPR119 (0.44) GPR119KDM4EALOX5APFEN1IDO1
SCHEMBL31654230 0.81 RORC (0.48) GPR119KDM4EIDO1USP30

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250215029-A1 STAT MODULATORS AND USES THEREOF RECLUDIX PHARMA, INC. 2025-07-03 — — US disclosed
WO-2023133336-A1 STAT MODULATORS AND USES THEREOF RECLUDIX PHARMA, INC. (US) 2023-07-13 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250215029-A1 STAT MODULATORS AND USES THEREOF STAT6, STAT3, STAT5A GPR119 399/4885KDM4E 1488/4885SPR 4363/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback