SCHEMBL25308409

SCHEMBL25308409

CCOP(=O)(Cc1ccc2c(c1)cc(C(=O)O)n2C(=O)OC(C)(C)C)OCC

nearest known ligand 0.39

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ NR1H2 P55055 19/20 0.39
▸ NR1H3 Q13133 3/20 0.39
▸ PTGES O14684 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22468625 0.90 NOD2 (0.40) NR1H2NR1H3
SCHEMBL31250412 0.90 NOD2 (0.40) NR1H2NR1H3
SCHEMBL22468607 0.87 CCR2 (0.37) PTGES
SCHEMBL28726665 0.83 SRD5A2 (0.43) NR1H2
SCHEMBL28726664 0.82 SRD5A2 (0.37) PTGES
SCHEMBL25263110 0.81 DPP4 (0.33) NR1H2NR1H3
SCHEMBL12042736 0.81 KDM4E (0.51) —
SCHEMBL27633493 0.80 NR1H2 (0.48) NR1H2NR1H3PTGES
SCHEMBL27633498 0.77 NR1H2 (0.41) NR1H2NR1H3PTGES
SCHEMBL12042743 0.76 KDM1A (0.41) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250215029-A1 STAT MODULATORS AND USES THEREOF RECLUDIX PHARMA, INC. 2025-07-03 — — US disclosed
EP-4463459-A1 STAT MODULATORS AND USES THEREOF Recludix Pharma, Inc. (US) 2024-11-20 — — EP disclosed
CN-118804917-A STAT modulators and uses thereof 瑞克鲁迪克斯制药股份有限公司 2024-10-18 — — CN disclosed
WO-2023133336-A1 STAT MODULATORS AND USES THEREOF RECLUDIX PHARMA, INC. (US) 2023-07-13 — — WO disclosed
WO-2023133336-A1 STAT MODULATORS AND USES THEREOF RECLUDIX PHARMA, INC. (US) 2023-07-13 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250215029-A1 STAT MODULATORS AND USES THEREOF STAT6, STAT3, STAT5A NR1H2 926/4885NR1H3 1115/4885PTGES 1118/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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