Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 8/20 | 0.58 |
| ▸ | TIPARP | Q7Z3E1 | 9/20 | 0.51 |
| ▸ | TNKS | O95271 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25309796 | 0.87 | TIPARP (0.67) | PARP1TIPARP | |
| SCHEMBL25309030 | 0.86 | TIPARP (0.63) | PARP1TIPARPTNKS | |
| SCHEMBL27434769 | 0.85 | TIPARP (0.53) | PARP1TIPARP | |
| SCHEMBL25309853 | 0.84 | PARP1 (0.64) | PARP1TIPARPSMN1; SMN2 | |
| SCHEMBL25309636 | 0.83 | TIPARP (0.59) | PARP1TIPARPTNKS | |
| SCHEMBL25310576 | 0.81 | PARP1 (0.59) | PARP1TIPARP | |
| SCHEMBL25262512 | 0.80 | PARP1 (0.61) | PARP1TIPARPTNKS | |
| SCHEMBL25309752 | 0.80 | PARP1 (0.59) | PARP1TIPARP | |
| SCHEMBL25227713 | 0.79 | TIPARP (0.74) | PARP1TIPARPHPGDSMN1; SMN2 | |
| SCHEMBL25697510 | 0.78 | TIPARP (0.60) | PARP1TIPARPHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023139536-A1 | (4-PIPERAZIN-1YL)-4-ALKYL-PHTHALAZIN-1(2H)-ONE COMPOUNDS AS PARP7 INHIBITORS | RHIZEN PHARMACEUTICALS AG (CH) | 2023-07-27 | — | — | WO | claimed |
| WO-2023139536-A1 | (4-PIPERAZIN-1YL)-4-ALKYL-PHTHALAZIN-1(2H)-ONE COMPOUNDS AS PARP7 INHIBITORS | RHIZEN PHARMACEUTICALS AG (CH) | 2023-07-27 | — | — | WO | disclosed |