Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TIPARP | Q7Z3E1 | 19/20 | 0.53 |
| ▸ | PARP1 | P09874 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.43 |
| ▸ | PARP16 | Q8N5Y8 | 1/20 | 0.43 |
| ▸ | PARP12 | Q9H0J9 | 1/20 | 0.43 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.43 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.43 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.43 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.43 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25309504 | 0.85 | PARP1 (0.58) | TIPARPPARP1 | |
| SCHEMBL27434496 | 0.83 | TIPARP (0.58) | TIPARPPARP1CYP2C9PARP14PARP16 | |
| SCHEMBL27434708 | 0.81 | TIPARP (0.53) | TIPARPPARP1CYP2C9PARP14PARP16 | |
| SCHEMBL27434851 | 0.81 | TIPARP (0.52) | TIPARPPARP1CYP2C9PARP14PARP16 | |
| SCHEMBL27434551 | 0.80 | TIPARP (0.57) | TIPARPPARP1CYP2C9PARP14PARP16 | |
| SCHEMBL27434555 | 0.79 | TIPARP (0.58) | TIPARPPARP1CYP2C9PARP14PARP16 | |
| SCHEMBL27434530 | 0.77 | TIPARP (0.68) | TIPARPPARP1TNKS2PARP2PARP3 | |
| SCHEMBL27434783 | 0.77 | TIPARP (0.55) | TIPARPPARP1CYP2C9PARP14PARP16 | |
| SCHEMBL27434643 | 0.77 | TIPARP (0.55) | TIPARPPARP1 | |
| SCHEMBL27440563 | 0.77 | TIPARP (0.49) | TIPARPPARP1CYP2C9PARP14PARP16 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240217968-A1 | PHARMACEUTICAL COMPOUND | Duke Street Bio Limited (GB) | 2024-07-04 | — | — | US | disclosed |
| US-20240217968-A1 | PHARMACEUTICAL COMPOUND | Duke Street Bio Limited (GB) | 2024-07-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240217968-A1 | PHARMACEUTICAL COMPOUND | F11, F12, ZYX | TIPARP 4717/4885PARP1 1174/4885CYP2C9 119/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.