Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 2/20 | 0.39 |
| ▸ | MMP7 | P09237 | 1/20 | 0.37 |
| ▸ | RAPGEF3 | O95398 | 1/20 | 0.34 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | STS | P08842 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2528829 | 0.92 | GAA (0.40) | AOC3GAALMNAL3MBTL1STS | |
| SCHEMBL2530920 | 0.88 | AURKA (0.39) | AURKARPS6KB1GAALMNAL3MBTL1 | |
| SCHEMBL2528867 | 0.85 | AOC3 (0.45) | AOC3MMP7GAALMNAL3MBTL1 | |
| SCHEMBL2530241 | 0.85 | GAA (0.52) | AOC3GAALMNAL3MBTL1KDM4E | |
| SCHEMBL2530437 | 0.85 | TSHR (0.39) | AOC3GAAKDM4EALDH1A1 | |
| SCHEMBL2532575 | 0.85 | KDM4E (0.38) | AOC3GAAKDM4EALDH1A1 | |
| SCHEMBL2531669 | 0.83 | AOC3 (0.43) | AOC3MMP7GAALMNAL3MBTL1 | |
| SCHEMBL2528064 | 0.82 | ALDH1A1 (0.39) | AOC3GAAL3MBTL1ALDH1A1 | |
| SCHEMBL2528446 | 0.82 | ALDH1A1 (0.39) | AOC3AURKARPS6KB1ALDH1A1 | |
| SCHEMBL2525203 | 0.82 | ALDH1A1 (0.37) | AOC3GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8039501-B2 | Synephrine derivatives useful as anti-inflammatory agents | UNIVERSITEIT GENT (BE) | 2011-10-18 | — | — | US | disclosed |
| US-20090029999-A1 | Synephrine derivatives useful as anti-inflammatory agents | UNIVERSITEIT GENT (BE) | 2009-01-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090029999-A1 | Synephrine derivatives useful as anti-inflammatory agents | HRH1, HRH3, HRH2 | AOC3 2105/4885MMP7 242/4885RAPGEF3 3202/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.