Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | STS | P08842 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | VDR | P11473 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2530985 | 0.92 | AOC3 (0.39) | GAAAOC3ALDH1A1STSL3MBTL1 | |
| SCHEMBL2530241 | 0.91 | GAA (0.52) | GAAMAPTAOC3ALDH1A1L3MBTL1 | |
| SCHEMBL2530437 | 0.91 | TSHR (0.39) | GAAAOC3ALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL2532575 | 0.87 | KDM4E (0.38) | GAAAOC3ALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL2528867 | 0.85 | AOC3 (0.45) | GAAMAPTAOC3ALDH1A1SMN1; SMN2 | |
| SCHEMBL2531669 | 0.83 | AOC3 (0.43) | GAAAOC3SMN1; SMN2L3MBTL1LMNA | |
| SCHEMBL2530920 | 0.82 | AURKA (0.39) | GAAMAPTALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL2529179 | 0.81 | MMP13 (0.36) | AOC3MEN1KMT2A | |
| SCHEMBL2530272 | 0.81 | MMP13 (0.40) | GAAAOC3ALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL2527332 | 0.81 | LMNA (0.39) | GAAMAPTAOC3ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8039501-B2 | Synephrine derivatives useful as anti-inflammatory agents | UNIVERSITEIT GENT (BE) | 2011-10-18 | — | — | US | disclosed |
| US-20090029999-A1 | Synephrine derivatives useful as anti-inflammatory agents | UNIVERSITEIT GENT (BE) | 2009-01-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090029999-A1 | Synephrine derivatives useful as anti-inflammatory agents | HRH1, HRH3, HRH2 | GAA 4431/4885MAPT 2834/4885AOC3 2105/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.