Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.42 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | PRKCH | P24723 | 1/20 | 0.39 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | EIF2AK4 | Q9P2K8 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31373403 | 0.83 | AOC3 (0.44) | AOC3OPRM1OPRL1PRKCHPRKCE | |
| SCHEMBL19117494 | 0.83 | AOC3 (0.49) | AOC3OPRM1OPRL1PRKCHPRKCE | |
| SCHEMBL16053043 | 0.83 | AOC3 (0.44) | AOC3OPRM1OPRL1PRKCHPRKCE | |
| SCHEMBL20953955 | 0.82 | KDM4E (0.55) | AOC3OPRM1OPRL1PRKCHPRKCE | |
| SCHEMBL26924381 | 0.81 | AOC3 (0.42) | AOC3OPRM1OPRL1PRKCHPRKCE | |
| SCHEMBL16048627 | 0.80 | POLB (0.53) | AOC3OPRM1OPRL1PRKCHPRKCE | |
| SCHEMBL15415088 | 0.80 | AOC3 (0.42) | AOC3OPRM1OPRL1PRKCHPRKCE | |
| SCHEMBL19105530 | 0.80 | OPRM1 (0.43) | AOC3OPRM1OPRL1PRKCHPRKCE | |
| SCHEMBL25075257 | 0.80 | AOC3 (0.44) | AOC3OPRM1OPRL1PRKCHPRKCE | |
| SCHEMBL20456745 | 0.80 | AOC3 (0.42) | AOC3OPRM1OPRL1PRKCHPRKCE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023139536-A1 | (4-PIPERAZIN-1YL)-4-ALKYL-PHTHALAZIN-1(2H)-ONE COMPOUNDS AS PARP7 INHIBITORS | RHIZEN PHARMACEUTICALS AG (CH) | 2023-07-27 | — | — | WO | disclosed |