SCHEMBL31373403

SCHEMBL31373403

O=C1CN(c2ncc(O)cn2)CCN1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AOC3 Q16853 1/20 0.44
OPRM1 P35372 3/20 0.42
OPRL1 P41146 3/20 0.42
GRIA1 P42261 1/20 0.39
PRKCH P24723 1/20 0.39
PRKCE Q02156 1/20 0.39
KDM4E B2RXH2 2/20 0.38
PIK3CA P42336 2/20 0.37
KMT2A Q03164 1/20 0.37
ALDH1A1 P00352 1/20 0.37
FGFR3 P22607 1/20 0.37
KDR P35968 1/20 0.37
CCNT1 O60563 1/20 0.36
CDK4 P11802 1/20 0.36
CCND1 P24385 1/20 0.36
CCND3 P30281 1/20 0.36
CDK9 P50750 1/20 0.36
CDK6 Q00534 1/20 0.36
SCN9A Q15858 1/20 0.36
GAK O14976 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19117494 0.83 AOC3 (0.49) AOC3OPRM1OPRL1PRKCHPRKCE
SCHEMBL25310063 0.83 AOC3 (0.44) AOC3OPRM1OPRL1PRKCHPRKCE
SCHEMBL16053043 0.83 AOC3 (0.44) AOC3OPRM1OPRL1PRKCHPRKCE
SCHEMBL15415088 0.83 AOC3 (0.42) AOC3OPRM1OPRL1GRIA1PRKCH
SCHEMBL16048627 0.83 POLB (0.53) AOC3OPRM1OPRL1PRKCHPRKCE
SCHEMBL20953955 0.82 KDM4E (0.55) AOC3OPRM1OPRL1PRKCHPRKCE
SCHEMBL26924381 0.81 AOC3 (0.42) AOC3OPRM1OPRL1GRIA1PRKCH
SCHEMBL20456745 0.80 AOC3 (0.42) AOC3OPRM1OPRL1PRKCHPRKCE
SCHEMBL19105530 0.80 OPRM1 (0.43) AOC3OPRM1OPRL1PRKCHPRKCE
SCHEMBL25075257 0.80 AOC3 (0.44) AOC3OPRM1OPRL1PRKCHPRKCE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119301115-A Compounds for enhancing read-through of genes containing premature stop codons and methods of making and using the same 赛诺菲美国服务公司 2025-01-10 CN disclosed