Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALPG | P10696 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 5/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25310088 | 1.00 | MAPT (0.43) | MAPTMEN1KMT2AKDM4EALPG | |
| SCHEMBL25878265 | 0.92 | MAPT (0.42) | MAPTMEN1KMT2AKDM4EALPG | |
| SCHEMBL29466310 | 0.85 | ANO1 (0.44) | KDM4EUSP30 | |
| SCHEMBL25883212 | 0.83 | AURKA (0.44) | MAPTRAB9AAURKAAURKBMAPK8 | |
| SCHEMBL25311803 | 0.82 | MAPT (0.45) | MAPTMEN1KMT2AKDM4EALPG | |
| SCHEMBL25311797 | 0.82 | MAPT (0.45) | MAPTMEN1KMT2AKDM4EALPG | |
| SCHEMBL25314126 | 0.81 | GSK3A (0.48) | MAPTRAB9AAURKAAURKBMAPK8 | |
| SCHEMBL25314121 | 0.81 | GSK3A (0.48) | MAPTRAB9AAURKAAURKBMAPK8 | |
| SCHEMBL27180231 | 0.80 | MEN1 (0.45) | MAPTMEN1KMT2AKDM4EALPG | |
| SCHEMBL25311732 | 0.78 | LANCL2 (0.57) | MAPTMEN1KMT2AKDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240101552-A1 | CARBONYL HETEROCYCLIC COMPOUND AND APPLICATION THEREOF | SHANGHAI PHARMACEUTICALS HOLDING CO., LTD. (CN) | 2024-03-28 | — | — | US | disclosed |
| EP-4215526-A1 | CARBONYL HETEROCYCLIC COMPOUND AND APPLICATION THEREOF | Shanghai Pharmaceuticals Holding Co., Ltd. (CN) | 2023-07-26 | — | — | EP | disclosed |
| WO-2022057932-A1 | CARBONYL HETEROCYCLIC COMPOUND AND APPLICATION THEREOF | 上海医药集团股份有限公司 | 2022-03-24 | — | — | WO | disclosed |
| WO-2022057928-A1 | CARBONYL HETEROCYCLIC COMPOUND AND APPLICATION THEREOF | 上海医药集团股份有限公司 | 2022-03-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240101552-A1 | CARBONYL HETEROCYCLIC COMPOUND AND APPLICATION THEREOF | LANCL2, CBS, LCP2 | MAPT 4180/4885MEN1 2222/4885KMT2A 3064/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.