Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA4 | P43681 | 12/20 | 0.58 |
| ▸ | CHRNB2 | P17787 | 9/20 | 0.58 |
| ▸ | CHRNB4 | P30926 | 9/20 | 0.58 |
| ▸ | CHRNA3 | P32297 | 9/20 | 0.58 |
| ▸ | CHRNA7 | P36544 | 9/20 | 0.58 |
| ▸ | AURKA | O14965 | 3/20 | 0.45 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.45 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.45 |
| ▸ | IKBKB | O14920 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.45 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.45 |
| ▸ | PRKCG | P05129 | 1/20 | 0.45 |
| ▸ | CDK1 | P06493 | 1/20 | 0.45 |
| ▸ | LYN | P07948 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | KIT | P10721 | 1/20 | 0.45 |
| ▸ | PIM1 | P11309 | 1/20 | 0.45 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.45 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29484579 | 1.00 | CHRNA4 (0.58) | CHRNA4CHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL29466341 | 0.92 | GSK3A (0.47) | CHRNA4CHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL25878075 | 0.92 | GSK3A (0.47) | CHRNA4CHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL25313124 | 0.88 | GSK3A (0.45) | CHRNA4CHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL25882455 | 0.86 | HRH4 (0.50) | CHRNA4CHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL25878312 | 0.84 | AURKA (0.49) | CHRNA4CHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL29466335 | 0.82 | GSK3A (0.50) | AURKAAURKBCHEK1IKBKBNPC1 | |
| SCHEMBL25882561 | 0.82 | GSK3A (0.50) | AURKAAURKBCHEK1IKBKBNPC1 | |
| SCHEMBL29466410 | 0.82 | MKNK1 (0.55) | AURKAAURKBCHEK1IKBKBNPC1 | |
| SCHEMBL25311322 | 0.82 | MKNK1 (0.55) | AURKAAURKBCHEK1IKBKBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240101552-A1 | CARBONYL HETEROCYCLIC COMPOUND AND APPLICATION THEREOF | SHANGHAI PHARMACEUTICALS HOLDING CO., LTD. (CN) | 2024-03-28 | — | — | US | disclosed |
| EP-4215526-A1 | CARBONYL HETEROCYCLIC COMPOUND AND APPLICATION THEREOF | Shanghai Pharmaceuticals Holding Co., Ltd. (CN) | 2023-07-26 | — | — | EP | disclosed |
| EP-4215526-A1 | CARBONYL HETEROCYCLIC COMPOUND AND APPLICATION THEREOF | Shanghai Pharmaceuticals Holding Co., Ltd. (CN) | 2023-07-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240101552-A1 | CARBONYL HETEROCYCLIC COMPOUND AND APPLICATION THEREOF | LANCL2, CBS, LCP2 | CHRNA4 4869/4885CHRNB2 4567/4885CHRNB4 4854/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.