Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 4/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2533769 | 0.88 | ACHE (0.40) | ACHEALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL2528932 | 0.88 | ACHE (0.47) | ACHEALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL12893358 | 0.86 | TSHR (0.38) | ACHEALDH1A1TSHRCHRNB2CHRNB4 | |
| SCHEMBL3905507 | 0.86 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2MEN1KMT2AHDAC1 | |
| SCHEMBL2531924 | 0.86 | ACHE (0.46) | ACHEALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL17921025 | 0.86 | CA1 (0.52) | ACHEMEN1KMT2ATSHRMGLL | |
| SCHEMBL12325598 | 0.85 | SMN1; SMN2 (0.40) | ALDH1A1SMN1; SMN2MEN1KMT2AHDAC1 | |
| SCHEMBL28802095 | 0.84 | CA1 (0.50) | ACHEMEN1KMT2AFDPSCA1 | |
| SCHEMBL2562127 | 0.84 | CA1 (0.50) | ACHEMEN1KMT2AFDPSCA1 | |
| SCHEMBL13471573 | 0.84 | CA1 (0.50) | ACHEMEN1KMT2AFDPSCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8461135-B2 | Boron-containing small molecules as anti-inflammatory agents | ANACOR PHARMACEUTICALS, INC. (US) | 2013-06-11 | — | — | US | claimed |
| US-8039450-B2 | Boron-containing small molecules as anti-inflammatory agents | ANACOR PHARMACEUTICALS, INC. (US) | 2011-10-18 | — | — | US | claimed |
| US-8337725-B2 | Vinylidene fluoride copolymers | SOLVAY SOLEXIS S.P.A. (IT) | 2012-12-25 | — | — | US | disclosed |
| US-20100133482-A1 | Vinylidene fluoride copolymers | SOLVAY SOLEXIS S.P.A. (IT) | 2010-06-03 | — | — | US | disclosed |
| US-5830936-A | THERMAL STABILIZERS FOR POLYOLEFINS AND ENGINEERING PLASTICS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1998-11-03 | — | — | US | disclosed |