Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 3/20 | 0.76 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.76 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.76 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.76 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.76 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.76 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.76 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.76 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.73 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.73 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.73 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.73 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.64 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.64 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.64 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.64 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.64 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.64 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.64 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13254437 | 1.00 | HDAC3 (0.76) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL5968936 | 1.00 | HDAC3 (0.76) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL17252159 | 1.00 | HDAC3 (0.76) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL9320350 | 1.00 | HDAC3 (0.76) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL26420478 | 0.98 | HDAC3 (0.75) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL6694936 | 0.93 | HDAC3 (0.72) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL9510547 | 0.93 | ENPP2 (0.71) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL9858666 | 0.93 | ENPP2 (0.71) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL675018 | 0.93 | ENPP2 (0.71) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| Methane SCHEMBL28141646 | 0.91 | HDAC3 (0.70) | HDAC3HDAC1HDAC2HDAC10HDAC11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8039669-B2 | Catalytic metathesis of secondary amides | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2011-10-18 | — | — | US | disclosed |
| US-20090299098-A1 | Catalytic Metathesis of Secondary Amides | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2009-12-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090299098-A1 | Catalytic Metathesis of Secondary Amides | NAAA, NAT1, NAT10 | HDAC3 1215/4885HDAC1 506/4885HDAC2 477/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.