Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25319677 | 0.88 | HTT (0.34) | MEN1CYP2C9CYP2C19KMT2AHSD17B10 | |
| SCHEMBL25318412 | 0.87 | HTT (0.46) | MEN1CYP2C9CYP2C19KMT2AHSD17B10 | |
| SCHEMBL25321980 | 0.82 | KDM4E (0.33) | MEN1CYP2C9CYP2C19KMT2AHSD17B10 | |
| SCHEMBL25943104 | 0.75 | MEN1 (0.36) | MEN1CYP2C9CYP2C19KMT2AHSD17B10 | |
| SCHEMBL25317896 | 0.72 | ALDH1A1 (0.32) | — | |
| SCHEMBL25318523 | 0.72 | — | — | |
| SCHEMBL25320409 | 0.72 | CASR (0.35) | — | |
| SCHEMBL25319377 | 0.69 | — | — | |
| SCHEMBL25317388 | 0.67 | — | — | |
| SCHEMBL21591627 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4466258-A1 | NEW BENZIMIDAZOLE PYRIDINE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2024-11-27 | — | — | EP | disclosed |
| WO-2023139085-A1 | NEW BENZIMIDAZOLE PYRIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2023-07-27 | — | — | WO | disclosed |