Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 5/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25321980 | 0.86 | KDM4E (0.33) | PTGS1PTGS2 | |
| SCHEMBL25317896 | 0.84 | ALDH1A1 (0.32) | PTGS1PTGS2 | |
| SCHEMBL25318523 | 0.83 | — | — | |
| SCHEMBL25949125 | 0.77 | PDE4B (0.42) | CASRPTGS1PTGS2PDE4BPDE3A | |
| SCHEMBL25319677 | 0.74 | HTT (0.34) | — | |
| SCHEMBL25318412 | 0.73 | HTT (0.46) | PTGS2 | |
| SCHEMBL25317388 | 0.73 | — | — | |
| SCHEMBL25427261 | 0.72 | PDE4B (0.31) | CASRPTGS1PTGS2PDE4BPDE3A | |
| SCHEMBL25317254 | 0.72 | MEN1 (0.32) | — | |
| SCHEMBL25317776 | 0.69 | CASR (0.34) | CASRPTGS1PTGS2PDE4BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023139085-A1 | NEW BENZIMIDAZOLE PYRIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2023-07-27 | — | — | WO | disclosed |