Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.53 |
| ▸ | BBOX1 | O75936 | 4/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | SLC22A16 | Q86VW1 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL29060116 | 0.97 | CA1 (0.50) | CA1BBOX1CYP2C19MEN1CYP1A2 | |
| Tetramethylammonium Ion SCHEMBL28621141 | 0.97 | CA1 (0.50) | CA1BBOX1CYP2C19MEN1CYP1A2 | |
| Bicarbonate SCHEMBL2277691 | 0.90 | BBOX1 (0.44) | CA1BBOX1CYP2C19MEN1CYP1A2 | |
| Bicarbonate SCHEMBL9003745 | 0.87 | TSHR (0.45) | CA1BBOX1CYP2C19MEN1CYP1A2 | |
| Bicarbonate SCHEMBL9003742 | 0.87 | BBOX1 (0.42) | CA1BBOX1CYP2C19MEN1CYP1A2 | |
| Acetic Acid SCHEMBL5844598 | 0.84 | BBOX1 (0.52) | CA1BBOX1CYP2C19POLBBLM | |
| Acetic Acid SCHEMBL557337 | 0.84 | BBOX1 (0.52) | CA1BBOX1CYP2C19POLBBLM | |
| Propionic Acid SCHEMBL5571644 | 0.84 | BBOX1 (0.46) | CA1BBOX1CYP2C19MEN1CYP1A2 | |
| Methacrylic Acid SCHEMBL540788 | 0.83 | CA4 (0.38) | CA1BBOX1CYP2C19MEN1CYP1A2 | |
| Methacrylic Acid SCHEMBL873041 | 0.81 | CA4 (0.36) | CA1BBOX1CYP2C19MEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116640039-A | Method for rectifying and separating toluene-methanol by using ethyl trimethyl ammonium acetate extractant | 沈阳化工大学 | 2023-08-25 | — | — | CN | claimed |
| EP-4114372-A1 | USE OF QX314 TO PREVENT SYMPATHOEXCITATION ASSOCIATED WITH ADMINISTRATION OF TRPV1 MODULATORS | Neucures, Inc. (US) | 2023-01-11 | — | — | EP | claimed |
| US-8575245-B2 | Tunable polymer compositions | NOVOMER, INC. (US) | 2013-11-05 | — | — | US | claimed |
| US-20110257296-A1 | TUNABLE POLYMER COMPOSITIONS | NOVOMER, INC. (US) | 2011-10-20 | — | — | US | claimed |
| WO-2010075232-A1 | TUNABLE POLYMER COMPOSITIONS | NOVOMER, INC. (US) | 2010-07-01 | — | — | WO | claimed |
| US-5393386-A | Method for preparing aqueous quaternary ammonium hydroxide solution | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1995-02-28 | — | — | US | claimed |
| US-20240156877-A1 | COMPOSITIONS AND USES THEREFOR | MELCARE MEDICAL PTY LTD (AU) | 2024-05-16 | — | — | US | disclosed |
| CN-116640039-A | Method for rectifying and separating toluene-methanol by using ethyl trimethyl ammonium acetate extractant | 沈阳化工大学 | 2023-08-25 | — | — | CN | disclosed |
| CN-116640039-A | Method for rectifying and separating toluene-methanol by using ethyl trimethyl ammonium acetate extractant | 沈阳化工大学 | 2023-08-25 | — | — | CN | disclosed |
| CN-116640039-A | Method for rectifying and separating toluene-methanol by using ethyl trimethyl ammonium acetate extractant | 沈阳化工大学 | 2023-08-25 | — | — | CN | disclosed |
| EP-4114372-A1 | USE OF QX314 TO PREVENT SYMPATHOEXCITATION ASSOCIATED WITH ADMINISTRATION OF TRPV1 MODULATORS | Neucures, Inc. (US) | 2023-01-11 | — | — | EP | disclosed |
| US-8575245-B2 | Tunable polymer compositions | NOVOMER, INC. (US) | 2013-11-05 | — | — | US | disclosed |
| US-20110257296-A1 | TUNABLE POLYMER COMPOSITIONS | NOVOMER, INC. (US) | 2011-10-20 | — | — | US | disclosed |
| US-7132473-B2 | Composition for forming porous film, porous film and method for forming the same, interlevel insulator film, and semiconductor device | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 2006-11-07 | — | — | US | disclosed |
| EP-1568744-A1 | COMPOSITION FOR POROUS FILM FORMATION, POROUS FILM, PROCESS FOR PRODUCING THE SAME, INTERLAYER INSULATION FILM AND SEMICONDUCTOR DEVICE | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 2005-08-31 | — | — | EP | disclosed |
| US-20040219372-A1 | Composition for forming porous film, porous film and method for forming the same, interlevel insulator film, and semiconductor device | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. | 2004-11-04 | — | — | US | disclosed |
| EP-0608545-B1 | Method for preparing aqueous quaternary ammonium hydroxide solution | MITSUBISHI GAS CHEMICAL CO (JP) | 1997-04-16 | — | — | EP | disclosed |
| US-5393386-A | Method for preparing aqueous quaternary ammonium hydroxide solution | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1995-02-28 | — | — | US | disclosed |
| EP-0608545-A1 | Method for preparing aqueous quaternary ammonium hydroxide solution | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1994-08-03 | — | — | EP | disclosed |
| EP-0327877-A2 | Peptide-renininhibitors | MERCK PATENT GmbH (DE) | 1989-08-16 | — | — | EP | disclosed |