Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21747533 | 0.87 | DPP4 (0.35) | KCNH2P2RX7 | |
| SCHEMBL23189791 | 0.82 | KDM1A (0.31) | KDM1A | |
| SCHEMBL16790608 | 0.81 | KCNH2 (0.36) | KDM1AKCNH2P2RX7 | |
| SCHEMBL24674667 | 0.81 | P2RX7 (0.35) | KDM1AKCNH2P2RX7 | |
| SCHEMBL23189901 | 0.79 | RORC (0.41) | KCNH2 | |
| SCHEMBL25237978 | 0.78 | — | — | |
| SCHEMBL24675499 | 0.78 | HSD17B10 (0.44) | KDM1AKCNH2P2RX7HSD17B10 | |
| SCHEMBL23547584 | 0.78 | MEN1 (0.39) | KDM1AKCNH2P2RX7HSD17B10 | |
| SCHEMBL24756929 | 0.76 | KCNH2 (0.34) | KDM1AKCNH2P2RX7 | |
| SCHEMBL23894814 | 0.76 | DPP4 (0.35) | KDM1AKCNH2P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023139085-A1 | NEW BENZIMIDAZOLE PYRIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2023-07-27 | — | — | WO | disclosed |