SCHEMBL25318115

SCHEMBL25318115

CC(O)CC(=O)N[C@@H]1C[C@H]2CC[C@@H](C1)N2C(=O)O

nearest known ligand 0.39

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.39
CYP3A4 P08684 1/20 0.38
HPGD P15428 1/20 0.38
CYP2C19 P33261 1/20 0.38
RAB9A P51151 1/20 0.38
CHRM1 P11229 2/20 0.36
MEN1 O00255 3/20 0.35
KMT2A Q03164 3/20 0.35
MAPK1 P28482 1/20 0.35
GAA P10253 1/20 0.34
ALDH1A1 P00352 2/20 0.34
AVPR1A P37288 2/20 0.34
MAPT P10636 1/20 0.34
LMNA P02545 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25318122 1.00 L3MBTL1 (0.39) L3MBTL1CYP3A4HPGDCYP2C19RAB9A
SCHEMBL25892543 0.81 CHRM1 (0.54) L3MBTL1CHRM1KMT2A
SCHEMBL25892538 0.81 CHRM1 (0.54) L3MBTL1CHRM1KMT2A
SCHEMBL30534534 0.81 CHRM1 (0.54) L3MBTL1CHRM1KMT2A
SCHEMBL3876900 0.78 LMNA (0.40) L3MBTL1CYP3A4CYP2C19MEN1KMT2A
SCHEMBL3876899 0.78 LMNA (0.40) L3MBTL1CYP3A4CYP2C19MEN1KMT2A
SCHEMBL3875019 0.78 MEN1 (0.38) L3MBTL1MEN1KMT2AMAPK1GAA
SCHEMBL3878767 0.78 MEN1 (0.38) L3MBTL1MEN1KMT2AMAPK1GAA
SCHEMBL3876909 0.78 MEN1 (0.38) L3MBTL1MEN1KMT2AMAPK1GAA
SCHEMBL3876907 0.78 MEN1 (0.38) L3MBTL1MEN1KMT2AMAPK1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023141323-A1 EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF BIOGEN MA INC. (US) 2023-07-27 WO disclosed