Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | SI | P14410 | 1/20 | 0.45 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | AHR | P35869 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29651245 | 0.76 | MGAM (0.44) | MGAMGAASIMGAM2TP53 | |
| SCHEMBL24729172 | 0.76 | MGAM (0.44) | MGAMGAASIMGAM2TP53 | |
| SCHEMBL21048592 | 0.70 | PIM1 (0.53) | MGAMGAASIMGAM2TP53 | |
| SCHEMBL7859854 | 0.70 | SLC6A4 (0.54) | MGAMGAASIMGAM2TP53 | |
| SCHEMBL17622901 | 0.70 | PIM1 (0.60) | MGAMGAASIMGAM2TP53 | |
| SCHEMBL19180067 | 0.69 | MGAM (0.41) | MGAMGAASIMGAM2TP53 | |
| SCHEMBL22864444 | 0.68 | ATM (0.48) | MGAMGAASIMGAM2PIM1 | |
| SCHEMBL31347809 | 0.68 | MGAM (0.58) | MGAMGAASIMGAM2PIM1 | |
| SCHEMBL21307359 | 0.68 | MGAM (0.58) | MGAMGAASIMGAM2PIM1 | |
| SCHEMBL30344459 | 0.68 | CYP2D6 (0.48) | MGAMGAASIMGAM2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023137771-A1 | METHOD FOR SYNTHESIZING α-ALKYL SUBSTITUTED INDOLE-3-CARBOXALDEHYDE COMPOUND | 苏州大学 | 2023-07-27 | — | — | WO | disclosed |