SCHEMBL31347809

SCHEMBL31347809

c1ccc2c(c1)-c1ccccc1C2(c1c[nH]c2ccccc12)c1c[nH]c2ccccc12

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGAM O43451 4/20 0.58
GAA P10253 4/20 0.58
SI P14410 4/20 0.58
MGAM2 Q2M2H8 4/20 0.58
HTR1A P08908 1/20 0.47
HTR2A P28223 1/20 0.47
HTR7 P34969 1/20 0.47
HTR6 P50406 1/20 0.47
PRKD3 O94806 2/20 0.44
ABL1 P00519 2/20 0.44
CCNB2 O95067 1/20 0.44
CCNE2 O96020 1/20 0.44
PRKCG P05129 1/20 0.44
PRKCB P05771 1/20 0.44
CDK1 P06493 1/20 0.44
PIM1 P11309 1/20 0.44
CDK4 P11802 1/20 0.44
CCNB1 P14635 1/20 0.44
PRKCA P17252 1/20 0.44
PRKACA P17612 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21307359 1.00 MGAM (0.58) MGAMGAASIMGAM2HTR1A
SCHEMBL17636725 0.80 MGAM (0.44) MGAMGAASIMGAM2HTR1A
Carbazole SCHEMBL1810585 0.78 ALDH1A1 (0.61) GAAPIM1ATMMEN1MAPT
SCHEMBL30870404 0.74 MGAM (1.00) MGAMGAASIMGAM2HTR1A
SCHEMBL20550167 0.74 MGAM (1.00) MGAMGAASIMGAM2HTR1A
SCHEMBL11897032 0.74 MGAM (0.68) MGAMGAASIMGAM2HTR1A
SCHEMBL29355276 0.73 KMT2A (0.56) MEN1MAPTKMT2ATDP1
SCHEMBL44942 0.73 KMT2A (0.56) MEN1MAPTKMT2ATDP1
SCHEMBL8594385 0.73 CFTR (0.51) MGAMGAASIMGAM2HTR1A
SCHEMBL21048592 0.72 PIM1 (0.53) MGAMGAASIMGAM2PRKD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12221556-B2 Hard-mask forming composition, method for manufacturing electronic component, and compound and resin TOKYO OHKA KOGYO CO., LTD. (JP) 2025-02-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12221556-B2 Hard-mask forming composition, method for manufacturing electronic component, and compound and resin RER1, SEM1, POP1 MGAM 4366/4885GAA 3467/4885SI 4776/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.