Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM1 | Q13255 | 11/20 | 0.56 |
| ▸ | GRM5 | P41594 | 11/20 | 0.56 |
| ▸ | WNT3A | P56704 | 1/20 | 0.50 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.45 |
| ▸ | NAMPT | P43490 | 1/20 | 0.45 |
| ▸ | HTR6 | P50406 | 1/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.44 |
| ▸ | GABRP | O00591 | 1/20 | 0.43 |
| ▸ | GABRD | O14764 | 1/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.43 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.43 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.43 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.43 |
| ▸ | GABRE | P78334 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29475585 | 1.00 | GRM1 (0.56) | GRM1GRM5WNT3APDK4CYP11B2 | |
| SCHEMBL903903 | 0.84 | GRM1 (0.56) | GRM1GRM5WNT3APDK4CYP11B2 | |
| SCHEMBL25320777 | 0.84 | NAMPT (0.57) | GRM1GRM5PDK4CYP11B2NAMPT | |
| SCHEMBL30366121 | 0.83 | GRM1 (0.52) | GRM1GRM5WNT3APDK4GPR119 | |
| SCHEMBL30899634 | 0.83 | GRM1 (0.52) | GRM1GRM5WNT3APDK4GPR119 | |
| SCHEMBL31039781 | 0.83 | GRM1 (0.55) | GRM1GRM5WNT3APDK4CYP11B2 | |
| SCHEMBL20266499 | 0.83 | GRM1 (0.64) | GRM1GRM5WNT3APDK4NAMPT | |
| SCHEMBL976835 | 0.83 | GRM1 (0.55) | GRM1GRM5WNT3APDK4CYP11B2 | |
| SCHEMBL13096687 | 0.83 | GRM1 (0.55) | GRM1GRM5WNT3APDK4CYP11B2 | |
| SCHEMBL29907164 | 0.83 | GRM1 (0.55) | GRM1GRM5WNT3APDK4CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240043395-A1 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF TLR SIGNALING | NEUROPORE THERAPIES, INC. | 2024-02-08 | — | — | US | disclosed |
| EP-4217342-A1 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF TLR SIGNALING | Neuropore Therapies, Inc. (US) | 2023-08-02 | — | — | EP | disclosed |
| CN-116507607-A | Compounds and compositions as modulators of TLR signaling | 神经孔疗法股份有限公司 | 2023-07-28 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240043395-A1 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF TLR SIGNALING | TLR3, TLR6, TLR4 | GRM1 110/4885GRM5 89/4885WNT3A 4341/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.