Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 18/20 | 0.53 |
| ▸ | MTNR1B | P49286 | 17/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25899800 | 0.86 | MTNR1A (0.48) | MTNR1AMTNR1BMAPTKDM4EALDH1A1 | |
| SCHEMBL30439531 | 0.86 | MTNR1A (0.48) | MTNR1AMTNR1BMAPTKDM4EALDH1A1 | |
| SCHEMBL25318719 | 0.83 | MAPT (0.51) | MTNR1AMTNR1BMAPTTHRBKDM4E | |
| SCHEMBL25318313 | 0.81 | MTNR1A (0.50) | MTNR1AMTNR1BMAPTTHRBKDM4E | |
| SCHEMBL25320268 | 0.73 | MTNR1A (0.66) | MTNR1AMTNR1BMAPTKDM4EALDH1A1 | |
| SCHEMBL8127311 | 0.72 | MTNR1A (0.76) | MTNR1AMTNR1B | |
| SCHEMBL30439647 | 0.71 | TP53 (0.41) | MTNR1AMTNR1BMAPTTHRB | |
| SCHEMBL25317235 | 0.71 | TP53 (0.41) | MTNR1AMTNR1BMAPTTHRB | |
| SCHEMBL8745753 | 0.70 | NQO1 (0.61) | MAPTTHRBKDM4EALDH1A1 | |
| SCHEMBL8133068 | 0.70 | MTNR1A (1.00) | MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023114858-A1 | BENZOFURAN AND BENZOTHIOPHENE PSYCHOPLASTOGENS AND USES THEREOF | DELIX THERAPEUTICS, INC. (US) | 2023-06-22 | — | — | WO | disclosed |