Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.60 |
| ▸ | HPGD | P15428 | 6/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.60 |
| ▸ | MAPT | P10636 | 5/20 | 0.60 |
| ▸ | THRB | P10828 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 5/20 | 0.58 |
| ▸ | NPC1 | O15118 | 4/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | STAT1 | P42224 | 1/20 | 0.55 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.54 |
| ▸ | STS | P08842 | 1/20 | 0.54 |
| ▸ | ACHE | P22303 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29699265 | 0.86 | KDM4E (0.60) | NQO1GAATP53KDM4EALDH1A1 | |
| SCHEMBL18766190 | 0.86 | KDM4E (0.60) | NQO1GAATP53KDM4EALDH1A1 | |
| SCHEMBL24627780 | 0.83 | MAPT (0.72) | GAATP53KDM4EALDH1A1HPGD | |
| SCHEMBL7141692 | 0.82 | KDM4E (0.55) | NQO1GAATP53KDM4EALDH1A1 | |
| SCHEMBL29944843 | 0.82 | KDM4E (0.55) | NQO1GAATP53KDM4EALDH1A1 | |
| Ocimarin SCHEMBL23752453 | 0.82 | HSD17B3 (0.79) | NQO1GAATP53KDM4EALDH1A1 | |
| SCHEMBL237672 | 0.81 | KDM4E (0.54) | NQO1GAATP53KDM4EALDH1A1 | |
| SCHEMBL8745770 | 0.81 | ALDH1A1 (0.57) | NQO1GAATP53KDM4EALDH1A1 | |
| SCHEMBL22733326 | 0.81 | KDM4E (0.77) | GAAKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL8745776 | 0.81 | NQO1 (0.59) | NQO1TP53KDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0663911-B1 | BENZOPYRANONES, METHOD OF PREPARING THEM AND THEIR USE | SCHWABE WILLMAR GMBH & CO (DE) | 1997-02-05 | — | — | EP | disclosed |
| US-5550129-A | THERAPY FOR NERVOUS SYSTEM AND PSYCHOLOGICAL DISORDERS | WILLMAR SCHWABE GMBH & CO. (DE) | 1996-08-27 | — | — | US | disclosed |
| EP-0663911-A1 | BENZOPYRANONES, METHOD OF PREPARING THEM AND THEIR USE. | SCHWABE WILLMAR GMBH & CO (DE) | 1995-07-26 | — | — | EP | disclosed |
| WO-1994008985-A1 | BENZOPYRANONES, METHOD OF PREPARING THEM AND THEIR USE | DR. WILLMAR SCHWABE GMBH & CO. (DE) | 1994-04-28 | — | — | WO | disclosed |