Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 1/20 | 0.33 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.32 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
| ▸ | OGA | O60502 | 2/20 | 0.32 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25319605 | 1.00 | PDGFRB (0.33) | PDGFRBPDGFRAAURKAKIF11OGA | |
| SCHEMBL30551153 | 1.00 | PDGFRB (0.33) | PDGFRBPDGFRAAURKAKIF11OGA | |
| Trifluoroacetic Acid SCHEMBL25321182 | 0.89 | OGA (0.33) | OGA | |
| SCHEMBL25322497 | 0.86 | CYP1A2 (0.40) | PDGFRBPDGFRAAURKAOGANOS3 | |
| SCHEMBL30551027 | 0.86 | CYP1A2 (0.40) | PDGFRBPDGFRAAURKAOGANOS3 | |
| SCHEMBL25322498 | 0.86 | CYP1A2 (0.40) | PDGFRBPDGFRAAURKAOGANOS3 | |
| SCHEMBL25323632 | 0.79 | GSK3B (0.43) | PDGFRBPDGFRAOGA | |
| SCHEMBL31578433 | 0.79 | GSK3B (0.43) | PDGFRBPDGFRAOGA | |
| SCHEMBL25323626 | 0.79 | GSK3B (0.43) | PDGFRBPDGFRAOGA | |
| SCHEMBL25322582 | 0.76 | CYP1A2 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250163048-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. | 2025-05-22 | — | — | US | disclosed |
| WO-2023146990-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |
| WO-2023146990-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250163048-A1 | COMPOUNDS AND METHODS OF USE | RB1, CYP1B1, REN | PDGFRB 2009/4885PDGFRA 2286/4885AURKA 2330/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.