Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.37 |
| ▸ | OGA | O60502 | 2/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.35 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31578433 | 1.00 | GSK3B (0.43) | GSK3BALDH1A1MAPK14MEN1CASP1 | |
| SCHEMBL25323626 | 1.00 | GSK3B (0.43) | GSK3BALDH1A1MAPK14MEN1CASP1 | |
| SCHEMBL30551480 | 0.89 | NPC1 (0.53) | GSK3BALDH1A1CASP1CYP1A2CYP2C19 | |
| SCHEMBL31578482 | 0.89 | NPC1 (0.53) | GSK3BALDH1A1CASP1CYP1A2CYP2C19 | |
| SCHEMBL25319298 | 0.89 | NPC1 (0.53) | GSK3BALDH1A1CASP1CYP1A2CYP2C19 | |
| SCHEMBL25319291 | 0.89 | NPC1 (0.53) | GSK3BALDH1A1CASP1CYP1A2CYP2C19 | |
| SCHEMBL31578497 | 0.81 | MAOA (0.43) | GSK3BALDH1A1CYP1A2NPC1RAB9A | |
| SCHEMBL25320626 | 0.81 | MAOA (0.43) | GSK3BALDH1A1CYP1A2NPC1RAB9A | |
| SCHEMBL25320632 | 0.81 | MAOA (0.43) | GSK3BALDH1A1CYP1A2NPC1RAB9A | |
| SCHEMBL25322585 | 0.81 | CYP1A2 (0.41) | CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4469455-A1 | COMPOUNDS AND METHODS OF USE | Tango Therapeutics, Inc. (US) | 2024-12-04 | — | — | EP | disclosed |
| WO-2023146990-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |